Association of ICU Admission Time, Age Stratification, and Clinical Frailty Scale With 30-Day Mortality in Geriatric Oncology Patients

NCT07825090 | Active Not Recruiting

• 1 other identifier: AOH2026-07/156
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Geriatric oncology patients frequently require intensive care admission and are at increased risk of adverse outcomes due to advanced age, frailty, and critical illness. Delays in admission from the emergency department to the intensive care unit (ICU) may further contribute to poor prognosis. This retrospective cohort study aims to evaluate the association of ICU admission time, age stratification, and Clinical Frailty Scale (CFS) score with 30-day mortality among geriatric cancer patients admitted from the emergency department to the Anesthesiology and Reanimation Intensive Care Unit. Secondary objectives include assessing the relationship of these factors with intensive care unit length of stay, hospital length of stay, and in-hospital mortality. The findings may contribute to improved risk stratification and optimization of critical care management in geriatric oncology patients.

Conditions

Cancer; Frailty; Mortality

Keywords

Geriatric Oncology; Clinical Frailty Scale; Emergency Department Boarding Time; İntensive Care Unit; 30-Day Mortality; ICU Admission Delay; Critical Care

Outcome Measures

Primary Outcomes (1)

• 30-Day All-Cause Mortality

  All cause mortality within 30 days after admission to the Anesthesiology and Reanimation Intensive Care Unit

  30 days

Secondary Outcomes (5)

• Emergency Department Boarding Time

  At intensive care unit admission

• Pre-Admission Clinical Frailty Scale (CFS) Score

  Baseline, prior to the acute illness leading to intensive care unit admission

• Clinical Frailty Scale Score According to Age Group

  Baseline, prior to the acute illness leading to intensive care unit admission.

• Intensive Care Unit Length of Stay

  At intensive care unit discharge

• 30-Day All-cause Mortality According to Age Group

  From the date of ICU admission until death from any cause, assessed up to 30 days

Study Arms (1)

Geriatric Oncology Patients

Patients aged 65 years and older with a diagnosis of cancer who were admitted from the emergency department to the Anesthesiology and Reanimation Intensive Care Unit between January 1, 2026 and July 1, 2026.

Other: Observation

Interventions

Observation OTHER

Retrospective observational assessment of emergency department boarding time, Clinical Frailty Scale score, age stratification, and their association with 30-day mortality in geriatric oncology patients admitted to the Anesthesiology and Reanimation Intensive Care Unit.

Geriatric Oncology Patients

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Geriatric oncology patients aged 65 years and older who were admitted from the Emergency Department to the Anesthesiology and Reanimation Intensive Care Unit between January 1, 2026 and July 1, 2026.

You may qualify if:

• Age ≥ 65 years
• Diagnosis of solid or hematologic malignancy
• Admission from the Emergency Department to the Anesthesiology and Reanimation Intensive Care Unit
• ICU admission between January 1, 2026 and July 1, 2026

You may not qualify if:

• Age \< 65 years
• Missing data regarding boarding time, Clinical Frailty Scale score, or 30-day mortality
• Readmission to the ICU during the same hospitalization
• Patients transferred from hospital wards or other ICUs

Sponsors & Collaborators

• Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital: lead

Study Sites (1)

Ankara Dr. Abdurrahman Yurtaslan Oncolgy Training and Research Hospital

Yenimahalle, Ankara, 0620, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Neoplasms; Frailty

Interventions

Observation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 9, 2026
• First Posted: September 17, 2026
• Study Start: January 1, 2026
• Primary Completion: July 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: September 17, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)