NCT07819318

Brief Summary

This study is a three-arm, randomized controlled pilot of a lung cancer screening intervention. The investigators will recruit participants ages 50-80 who are likely to meet lung cancer screening guidelines. After eligibility screening, participants will be randomized to one of three educational interventions regarding lung cancer. Lung cancer screening outcomes will be assessed.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
11mo left

Started Oct 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 8, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 14, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

October 15, 2026

Expected
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2027

2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2027

Last Updated

September 14, 2026

Status Verified

September 1, 2026

Enrollment Period

9 months

First QC Date

September 8, 2026

Last Update Submit

September 8, 2026

Conditions

Lung Cancer Screening

Keywords

tobaccosmokinglung cancercancer screening

Outcome Measures

Primary Outcomes (1)

  • Number of Participants with Completion of Lung Cancer Screening

    Self-reported completion of low dose chest CT for lung cancer screening during the study follow-up period

    3 months

Secondary Outcomes (2)

  • Number of Participants with Clinician Discussion on Lung Cancer Screening

    3 months

  • Number of Participants with Change in Intent to obtain lung cancer screening

    3 months

Study Arms (3)

Notification of Eligibility

NO INTERVENTION

Participants receive notification of eligibility for lung cancer screening with a recommendation to discuss with their health care provider

Video/Brochure

EXPERIMENTAL

Participants receive an animated video with accompanying guide.

Behavioral: Video/Brochure

Video/Brochure/Follow-up Call

EXPERIMENTAL

Participants receive an animated video video, an accompanying guide, and a call with a community outreach specialist/community health worker.

Behavioral: Video/Brochure/Follow-up Call

Interventions

Video/BrochureBEHAVIORAL

Brief animated video that covers the basics of lung cancer screening and shows shared decision-making. An accompanying brochure uses images and information from the video to reinforce concepts (delivered via PDF or mail, per participant preference).

Video/Brochure
Video/Brochure/Follow-up CallBEHAVIORAL

Brief animated video that covers the basics of lung cancer screening and shows shared decision-making. An accompanying brochure uses images and information from the video to reinforce concepts (delivered via PDF or mail, per participant preference). A follow-up call with a community outreach specialist/community health worker is made 1-2 weeks after the initial intervention to check in on participant plans regarding lung cancer screening and to assist with any barriers.

Video/Brochure/Follow-up Call

Eligibility Criteria

Age50 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Existing record within the Johns Hopkins medical system
  • Age 50-80
  • Current tobacco use OR cessation within the past 15 years
  • pack year history of smoking
  • No chest CT imaging within the past 18 months
  • English speaking
  • Willing to complete the study procedures, which include questionnaires and possibly a follow-up call

You may not qualify if:

  • Not meeting eligibility criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

SmokingLung Neoplasms

Interventions

Videotape Recording

Condition Hierarchy (Ancestors)

BehaviorRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Tape RecordingAudiovisual AidsEducational TechnologyTechnologyTechnology, Industry, and AgricultureTelevision

Study Officials

  • Alejandra Ellison-Barnes, MD, MPH

    Johns Hopkins University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Alejandra Ellison-Barnes, MD, MPH

CONTACT

410-955-5000aelliso6@jhmi.edu

Heidi Hutton, PhD

CONTACT

443-287-2874hhutton@jhmi.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 8, 2026

First Posted

September 14, 2026

Study Start (Estimated)

October 15, 2026

Primary Completion (Estimated)

June 30, 2027

Study Completion (Estimated)

August 30, 2027

Last Updated

September 14, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share