NCT07639255

Brief Summary

This is an optimization pathway for lung cancer screening programs. Enrolled programs will undergo an audit for elements associated with improved quality and retention of patients in the screening process. A feedback report is delivered to identify priorities for process improvement.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
330

participants targeted

Target at P75+ for not_applicable

Timeline
22mo left

Started Apr 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

17 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress43%
Apr 2025Jun 2028

Study Start

First participant enrolled

April 1, 2025

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

June 5, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 10, 2026

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

July 1, 2026

Status Verified

June 1, 2026

Enrollment Period

2.2 years

First QC Date

June 5, 2026

Last Update Submit

June 27, 2026

Conditions

Lung Cancer Screening

Outcome Measures

Primary Outcomes (1)

  • Change in Quality Improvement Lung Cancer Screening (QUILS) Index Assessment Score

    The QUILS Index Assessment is a program-level measure of lung cancer screening implementation quality. Scores range from 0 to 95, with a higher score indicating higher quality implementation of lung cancer screening practices. The outcome measure is the change in total QUILS Index score from Baseline to 12 months.

    One year following study start up and initial assessment.

Study Arms (1)

QUILS Kentucky Coalition Initative

OTHER
Other: QUILS System

Interventions

QUILS SystemOTHER

Implementation initiative involving statewide coalition engagement surveys, interviews, educational outreach, and collaborative activities designed to improve awareness, coordination, policy support, and implementation of equitable and high-quality lung screening programs.

QUILS Kentucky Coalition Initative

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants in Lung Cancer Screening Program, including physicians, nurses, administrators and other staff responsible for the conduct of the program.
  • Willing to participate in the QUILS Index Assessment Survey process
  • Willing to participate in the QUILS Audit Feedback presentations Willing to participate in formative evaluation interviews

You may not qualify if:

  • Unwilling to participate in the QUILS Index Assessment Survey process
  • Unwilling to participate in the QUILS Audit Feedback presentations
  • Unwilling to participate in formative evaluation interviews

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

King's Daughter's Medical Center

Ashland, Kentucky, 41101, United States

RECRUITING

Taylor Regional Hospital

Campbellsville, Kentucky, 42718, United States

RECRUITING

St. Elizabeth Healthcare

Edgewood, Kentucky, 41017, United States

RECRUITING

Georgetown Cancer Treatment Cancer

Georgetown, Kentucky, 40324, United States

RECRUITING

TJ Samson Community Hospital

Glasgow, Kentucky, 42141, United States

RECRUITING

Hazard Appalachian Regional Healthcare Medical Center

Hazard, Kentucky, 41701, United States

RECRUITING

Lexington VA Health Care System

Lexington, Kentucky, 40502, United States

RECRUITING

St. Joseph Health (Catholic Health Initiatives)

Lexington, Kentucky, 40504, United States

RECRUITING

University of Kentucky Markey Cancer Center

Lexington, Kentucky, 40536, United States

RECRUITING

The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States

RECRUITING

Meadowview Regional Medical Center

Maysville, Kentucky, 41056, United States

RECRUITING

Saint Claire Regional Medical Center

Morehead, Kentucky, 40351, United States

RECRUITING

Rockcastle Regional Hospital

Mount Vernon, Kentucky, 40456, United States

RECRUITING

Owensboro Health Mitchell Memorial Cancer Center

Owensboro, Kentucky, 42303, United States

RECRUITING

Mercy Health - Paducah Cancer Center

Paducah, Kentucky, 42003, United States

RECRUITING

Lake Cumberland Regional Hospital

Somerset, Kentucky, 42501, United States

RECRUITING

Clark Regional Medical Center

Winchester, Kentucky, 40391, United States

RECRUITING

Study Officials

  • Timothy W Mullett, MD

    University of Kentucky

    STUDY CHAIR

Central Study Contacts

Joseph Alexander, MD

CONTACT

8593230892joseph.alexander@uky.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 5, 2026

First Posted

June 10, 2026

Study Start

April 1, 2025

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

June 1, 2028

Last Updated

July 1, 2026

Record last verified: 2026-06

Locations

US(17)