MB2 Canals in Pediatric Maxillary First Molars

NCT07808489 | Completed

• 1 other identifier: 2023-12/02
• Study Type: interventional
• Target: 77
• Locations: 1 country
• Sites: 1

Brief Summary

This study examined how often an additional root canal, known as the second mesiobuccal canal (MB2), could be found in the upper first permanent molars of children aged 10-15 years. During root canal treatment, an endodontist followed a step-by-step approach using a standard clinical examination, magnifying loupes, a dental microscope, and, when clinically necessary, three-dimensional dental imaging. The study evaluated how much each step contributed to locating and confirming the canal.

Conditions

Root Canal Therapy

Keywords

second mesiobuccal canal; permanent maxillary first molar; pediatric dentistry; root canal therapy; microscopy; ultrasonics; cone-beam computed tomography

Outcome Measures

Primary Outcomes (1)

• Cumulative Clinical Confirmation Yield of MB2 Canals

  Proportion of all treated teeth in which an MB2 canal met the predefined clinical confirmation criteria by the end of the stepwise protocol.

  Periprocedural (at completion of the stepwise MB2 clinical confirmation protocol during root canal treatment)

Secondary Outcomes (4)

• Initial Clinical Confirmation Yield During Direct Clinical Examination

  Periprocedural (immediately after completion of Stage 1 direct clinical examination during root canal treatment)

• Incremental Clinical Confirmation Yield Under Dental Loupes

  Periprocedural (immediately after completion of Stage 2 selective dentin removal under magnifying dental loupes during root canal treatment)

• Incremental Clinical Confirmation Yield Under a Dental Operating Microscope

  Periprocedural (immediately after completion of Stage 3 selective dentin removal under a dental operating microscope during root canal treatment)

• Incremental Clinical Confirmation Yield Following CBCT-Guided Re-examination

  Periprocedural (immediately after completion of Stage 4 clinically indicated CBCT-guided re-examination during root canal treatment)

Study Arms (1)

Stepwise MB2 Clinical Confirmation Protocol

EXPERIMENTAL

Participants underwent a predefined stepwise protocol for the clinical confirmation of the second mesiobuccal canal during primary root canal treatment of a permanent maxillary first molar. The protocol progressed from direct clinical examination without magnification to selective dentin removal under dental loupes and then under a dental operating microscope. Clinically indicated CBCT assessment and CBCT-guided re-examination were considered only when clinical confirmation had not been achieved during the first three stages. Once an MB2 canal was clinically confirmed, no subsequent confirmation stage was undertaken.

Diagnostic Test: Stepwise MB2 Clinical Confirmation Protocol

Interventions

Stepwise MB2 Clinical Confirmation Protocol DIAGNOSTIC_TEST

The MB2 canal was assessed sequentially using: Stage 1, direct clinical examination without magnification; Stage 2, selective dentin removal under dental loupes at ×4 magnification using ultrasonic instrumentation; Stage 3, selective dentin removal under a dental operating microscope at ×16 magnification; and Stage 4, clinically indicated CBCT assessment followed, when radiographic evidence of an MB2 canal was observed, by CBCT-guided re-examination under the dental operating microscope. Clinical confirmation required identification of an orifice separate from the MB1 canal and negotiation of the canal to the working length.

Stepwise MB2 Clinical Confirmation Protocol

Eligibility Criteria

• Age: 10 Years - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Pediatric patients aged 10-15 years requiring primary root canal treatment of a permanent maxillary first molar
• A clinically and radiographically restorable study tooth
• "Positive" or "definitely positive" behavior according to the Frankl Behavior Rating Scale
• No systemic condition contraindicating the planned endodontic treatment
• No known hypersensitivity to the local anesthetics, irrigation solutions, or other materials used during treatment
• Written informed consent provided by a parent or legal guardian

You may not qualify if:

• Previous root canal treatment or endodontic intervention involving the study tooth
• Presence of a vertical root fracture, root resorption, or pre-existing perforation in the study tooth

Sponsors & Collaborators

• Sümeyra Akkoç: lead

Study Sites (1)

Kütahya Health Sciences University, Faculty of Dentistry

Kütahya, Kütahya, 43100, Turkey (Türkiye)

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor of Pediatric Dentistry

Study Record Dates

• First Submitted: September 2, 2026
• First Posted: September 8, 2026
• Study Start: October 1, 2023
• Primary Completion: September 24, 2024
• Study Completion: October 1, 2024
• Last Updated: September 8, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)