Early Postoperative Pain After Cardiac Surgery

NCT07804732 | Completed

• 1 other identifier: 2026-242
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study will evaluate factors that may be associated with pain during the first 24 hours after open heart surgery. The study will include adult patients who underwent coronary artery bypass grafting (CABG), heart valve surgery, or combined cardiac surgery. Researchers will retrospectively review existing medical records to examine whether patient characteristics, preoperative anxiety and depression, and factors related to surgery and anesthesia are associated with postoperative pain. The study will also evaluate postoperative nausea and vomiting and the need for additional pain medication. No treatment or intervention will be assigned to participants as part of this study. Study data will be collected retrospectively from existing medical records.

Conditions

Postoperative Nausea and Vomiting (PONV)

Keywords

Cardiac Surgery; Postoperative Pain; Preoperative Anxiety; Preoperative Depression; Multimodal Analgesia; Postoperative Nausea and Vomiting; Rescue Analgesia; Numeric Rating Scale

Outcome Measures

Primary Outcomes (1)

• Mean Postoperative Pain Score During the First 24 Hours

  Postoperative pain will be assessed at rest using the 0-10 Numeric Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst pain. NRS scores recorded at 0, 3, 6, 12, and 24 hours after the initial postoperative assessment in the intensive care unit will be used to calculate the mean pain score (NRSmean) for the first 24 postoperative hours.

  First 24 hours after surgery

Study Arms (1)

Cardiac Surgery Cohort

Adult patients who underwent open cardiac surgery, including coronary artery bypass grafting (CABG), valve surgery, or combined cardiac surgery, between April 1, 2025 and April 1, 2026. Existing medical records will be retrospectively reviewed to evaluate early postoperative pain and related outcomes. No study-specific treatment or intervention will be assigned by the investigators.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients who underwent open cardiac surgery, including coronary artery bypass grafting (CABG), valve surgery, or combined cardiac surgery, at a tertiary care center between April 1, 2025 and April 1, 2026. Eligible patients will be identified retrospectively from existing electronic medical records according to the predefined inclusion and exclusion criteria.

You may qualify if:

• Age ≥18 years
• Underwent open cardiac surgery, including coronary artery bypass grafting (CABG), valve surgery, or combined cardiac surgery
• Complete perioperative and postoperative pain data available in the medical records

You may not qualify if:

• Incomplete medical records
• Reoperation within the first 24 postoperative hours
• Chronic opioid use
• Cognitive impairment

Sponsors & Collaborators

• Antalya Training and Research Hospital: lead

Study Sites (1)

SBU Antalya Training and Research Hospital

Antalya, 07100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Postoperative Nausea and Vomiting; Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Nausea; Signs and Symptoms, Digestive; Signs and Symptoms; Vomiting; Pain; Neurologic Manifestations

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 1, 2026
• First Posted: September 4, 2026
• Study Start: August 10, 2026
• Primary Completion: September 5, 2026
• Study Completion: September 7, 2026
• Last Updated: October 1, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)