Spinal Alignment as a Predictor of Functional Performance in Individuals With Upper Cross Syndrome: A Secondary Analysis of a Randomized Controlled Trial

NCT07786415 | Not Yet Recruiting

• 1 other identifier: IRB#17/5/2025-2026
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to explore the relationship between spinal alignment and functional performance in individuals with upper cross syndrome following a combined breathing and manual therapy program. It is designed as a secondary analysis of data obtained from a previously conducted randomized controlled trial, with the addition of objective spinal measurements using the Spinal Mouse device. Functional performance will be assessed using standardized tests such as the 6-minute walk test and the timed up and go test. Statistical analysis will include correlation and regression models to determine whether spinal alignment parameters can predict functional outcomes. The findings are expected to provide insight into the biomechanical role of posture in functional recovery among individuals with upper cross syndrome.

Conditions

Upper Cross Syndrome; Spinal Alignment; Functional Performance

Keywords

upper cross syndrome; Spinal alignment; Functional performance

Outcome Measures

Primary Outcomes (2)

• Spinal Alignment: Thoracic kyphosis

  Kyphosis is the forward curvature of the thoracic spine.It will be measured by The Spinal Mouse ( a hand-held, computer-assisted medical device used to measure spinal curvature, posture, and segmental mobility without radiation )

  Pre and post 8 weeks

• Spinal Alignment: Lumbar lordosis

  inward curvature of the spine when this curve becomes excessive or diminished, it can lead to discomfort and postural issues.It will be measured by The Spinal Mouse ( a hand-held, computer-assisted medical device used to measure spinal curvature, posture, and segmental mobility without radiation )

  Pre and post 8 weeks

Secondary Outcomes (2)

• Functional Performance: 6-Minute Walk Test (6MWT)

  Pre and post 8 weeks

• Functional Performance: Timed Up and Go Test (TUG)

  Pre and post 8 weeks

Study Arms (2)

Experimental group

EXPERIMENTAL

Other: The experimental group will perform ujjayi pranayama and osteopathic manipulative tratment

Control group

ACTIVE COMPARATOR

Other: control group will perform osteopathic manipulative treatment only

Interventions

The experimental group will perform ujjayi pranayama and osteopathic manipulative tratment OTHER

The experimental group will perform ujjayi pranayama and osteopathic manipulative treatment for 45 min sessions, 5 times a week for 8 weeks

Experimental group

control group will perform osteopathic manipulative treatment only OTHER

control group will perform osteopathic manipulative treatment only for 45 min sessions, 5 times a week for 8 weeks

Control group

Eligibility Criteria

• Age: 20 Years - 29 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Full time college students of age 20-29 years.
• Subjects who have upper cross syndrome according to REEDCO posture assessment.
• Subjects who not receiving medical treatment for respiratory diseases .
• Subjects who have clean family medical history.

You may not qualify if:

• Subjects who engaged in additional exercise in two weeks, which was likely to affect the results of the research .
• Individuals with a history of spine, shoulder fractures, surgery, or other disease.
• Individuals with severe cardia-cerebrovascular disease.
• Individuals who will have difficulty to follow-up testing).
• Neurologic and psychiatric disorders (who can not understand the research project ).
• Individuals with congenital deformities

Sponsors & Collaborators

• Al-Zaytoonah University of Jordan: lead

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type Preus

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor doctor

Study Record Dates

• First Submitted: August 19, 2026
• First Posted: August 26, 2026
• Study Start: August 25, 2026
• Primary Completion (Estimated): October 25, 2026
• Study Completion (Estimated): October 25, 2026
• Last Updated: August 26, 2026

Record last verified: 2026-08