NCT07588061

Brief Summary

This randomized controlled trial aims to compare the effects of Maitland mobilization combined with Kendall exercises versus Kendall exercises alone on pain and postural alignment in adults with Upper Cross Syndrome (UCS). Upper Cross Syndrome is characterized by muscle imbalance leading to forward head posture, rounded shoulders, and increased thoracic kyphosis. The study will evaluate pain intensity, craniovertebral angle, thoracic kyphosis, and rounded shoulder posture

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 6, 2026

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

May 2, 2026

Completed
12 days until next milestone

First Posted

Study publicly available on registry

May 14, 2026

Completed
23 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 6, 2026

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 8, 2026

Completed
Last Updated

May 20, 2026

Status Verified

May 1, 2026

Enrollment Period

2 months

First QC Date

May 2, 2026

Last Update Submit

May 17, 2026

Conditions

Outcome Measures

Primary Outcomes (4)

  • Thoracic Kyphosis Assessed With Flexicurve Ruler

    Thoracic kyphosis will be measured using a flexicurve ruler. The spinous processes of C7 and T12 will be palpated and marked. The flexicurve ruler will mold along the thoracic curvature between these landmarks, and the curve will be transferred onto paper. . Based on previously published literature, thoracic kyphosis is considered 'normal' between 20 and 40°. Where this exceeds 40°, the curvature is described as hyperkyphosis.

    baseline to last week (8 week)

  • Forward Head Posture Assessed with Protractor mobile application

    Forward head posture will be assessed by measuring the craniovertebral angle (CVA) using the protractor mobile application. Measuring CVA from a lateral view by drawing a line from the ear tragus to the spinous process of the seventh cervical vertebra and a horizontal reference line through C7. The angle formed between these two lines will represent the craniovertebral angle.A reduced craniovertebral angle indicates increased forward head posture, with values less than 50° commonly used to identify this condition

    baseline to last week (8 week)

  • Rounded Shoulder Assessed with Vernier Caliper

    Rounded shoulder posture was assessed using a vernier caliper. Participants were positioned supine on a firm couch with arms relaxed by their sides. The vertical distance between the posterolateral edge of the acromion process and the couch surface was measured using a vernier caliper. Measurements will be taken bilaterally; an acromion-to-couch distance greater than 2.5cm will be considered indicative of rounded shoulder posture.

    baseline to last week (8 week)

  • Visual Analogue Scale

    The intensity of the pain will be measured with the help of the Visual Analogue Scale (VAS). The VAS is a 10-cm horizontal line with two opposite endpoints marked with the following words: "no pain" at one end and "worst imaginable pain" at the other. The patient will then mark a point on the line that they feel most accurately reflects their current pain. The distance in centimeters or millimeters between the "no pain" point and the patient's mark will be taken as the measure of the patient's pain.

    baseline to last week

Study Arms (2)

Maitland Mobilization Combined With Kendall Exercises

EXPERIMENTAL

Participants in this group will receive Maitland mobilization techniques applied to the cervical and thoracic spine, combined with Kendall exercises targeting postural correction. Mobilization will be performed by a trained physiotherapist using graded oscillatory techniques. The exercise program will focus on strengthening weak postural muscles and stretching tight musculature associated with upper cross syndrome.

Other: Kendall Exercises combined Maitland Mobilization

Kendall Exercises Alone

ACTIVE COMPARATOR

Participants in this group will receive a Kendall exercise program focusing on postural correction. The program includes strengthening of weak muscles and stretching of tight muscles associated with upper cross syndrome.

Other: Kendall Exercise alone

Interventions

Group A (Experimental) received Kendall exercises combined with Maitland mobilization, including strengthening of deep cervical flexors, lower trapezius, and serratus anterior, along with stretching of upper trapezius, levator scapulae, and pectoralis major/minor. Maitland mobilization was applied to the cervical and upper thoracic spine using central and unilateral PA oscillations for 50-60 seconds per segment at 2-3 oscillations per second, in addition to warm-up (cervical AROM and shoulder mobility exercises) and cool-down (stretching and diaphragmatic breathing).

Maitland Mobilization Combined With Kendall Exercises

Participants in this group will receive a structured Kendall exercise program only, without any manual therapy or mobilization techniques. The intervention will focus on postural correction through strengthening of weakened muscles (deep cervical flexors, scapular retractors) and stretching of tight muscles (pectoralis major/minor, upper trapezius, levator scapulae) associated with upper cross syndrome.

Kendall Exercises Alone

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18 to 45 years
  • Neck and/or upper thoracic pain for a duration of \> 6 weeks
  • Pain Severity: VAS \> 5 (Afzal, Noor, Mumtaz, Bashir, \& Saqulain, 2023)
  • Pain exacerbated by prolonged postures
  • Adults diagnosed with Upper Cross Syndrome
  • Diagnostic criteria: Upper Cross Syndrome will be diagnosed when individuals demonstrate: thoracic kyphosis \> 40°, craniovertebral angle \< 50°, and acromion-to-couch distance \> 2.5 cm based on established normative values.

You may not qualify if:

  • History of neck or shoulder surgery or trauma
  • Inflammatory conditions such as rheumatoid arthritis or gout
  • Pregnancy
  • Neurological conditions affecting upper limb function, and
  • Cardiovascular Problems
  • Congenital issues i.e.; torticollis, and scoliosis
  • Disc prolapse and other spine issues
  • Currently taking any medication or taking physical therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ibadat International University, Islamabad (Iiui)

Peshawar, KPK, 25000, Pakistan

RECRUITING

Related Publications (38)

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    BACKGROUND
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  • Afzal, H., Noor, R., Mumtaz, N., Bashir, M. S., & Saqulain, G. (2023). Effects of Kendall exercise vs. Gong's mobilization on pain, range of motion, function, and strength in cases with text neck syndrome. Iranian Rehabilitation Journal, 21(3), 411-420.

    BACKGROUND

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type Preus

Central Study Contacts

Naeem Ullah, DPT, MS-PT MSK

CONTACT

Fatima Amjad, DPT, MS-PT Sports, PHD Scholer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Two-arm parallel group randomized controlled trial
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 2, 2026

First Posted

May 14, 2026

Study Start

April 6, 2026

Primary Completion

June 6, 2026

Study Completion

June 8, 2026

Last Updated

May 20, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations