NCT07785973|RecruitingDMC
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Sponsor study identifier
interventional
30
1 country
1
Study Start
August 1, 2026
Actual (reported)Primary Completion
August 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
August 10, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success of root canal treatment is affected by the correct choice of clinical protocol. These factors are dependent on the sanitization process (instrumentation, irrigating solution, irrigating strategies, and intracanal dressing) the apical limit of the root canal preparation and obturation, and the quality of the sealer. The challenges affecting the healing process of endodontically treated teeth include control of the inflammation of pulp or infectious processes and simultaneous neutralization of unpredictable provocations to the periapical tissue.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 10, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 1, 2026
Actual (reported)August 21, 2026
Actual (reported)August 25, 2026
Actual (reported)August 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
August 10, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Treatment of Postoperative Pain
Patients will be evaluated for postoperative pain via (NRS) to record the intensity of pain.as follows: 0 reading represents "no pain" ; 1- 3 reading represents "mild pain" ; 4- 6 reading represents "moderate pain" and 7- 10 reading represents "severe pain".
from 0 hours to 2 weeks after the procedure
Periapical Healing
After 6 months to 12 months
About 15 cases will undergo the AH plus sealer during obturation After complete preparation of the root canal system
About 15 cases will undergo the Neo Sealer FLO during obturation After complete preparation of the root canal system
to evaluate and compare postoperative pain and periapical healing after root canal treatment using two different base endodontic sealers: * NeoSEALER Flo * AH plus Resin sealer
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Minia University, Faculty of Dentistry
Minya, Egypt
Maged Mohamed Negm, M.D
Professor of Endodontics, Faculty of Dentistry,Cairo University
First Submitted
August 21, 2026
First Posted
August 25, 2026
Study Start
August 1, 2026
Actual (reported)Primary Completion
August 1, 2027
EstimatedEvaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination
Contact the study team to confirm eligibility.
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
August 10, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
August 25, 2026
Record last verified: 2026-08
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Source: ClinicalTrials.gov.
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