NCT07776587

Brief Summary

The purpose of this study is to learn whether a yoga therapy program can improve quality of life and reduce symptoms in people undergoing stem cell transplantation compared with an enhanced standard care physical activity program.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for not_applicable cancer

Timeline
63mo left

Started Feb 2027

Longer than P75 for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 17, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 20, 2026

Completed
6 months until next milestone

Study Start

First participant enrolled

February 1, 2027

Expected
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 13, 2030

2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 13, 2032

Last Updated

August 20, 2026

Status Verified

August 1, 2026

Enrollment Period

3.2 years

First QC Date

August 17, 2026

Last Update Submit

August 17, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Safety and Adverse Events (AEs)

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

    Through study completion; an average of 1 year

Study Arms (2)

SC: Enhanced Stand of Care Group

EXPERIMENTAL

In the experimental \& control interventions: participants will receive up to 3 sessions per week, for a total of up to 10 weeks or 20 sessions, whichever comes first

Other: Yoga Therapy (YT)

YT: Yoga Group

EXPERIMENTAL

In the experimental \& control interventions: participants will receive up to 3 sessions per week, for a total of up to 10 weeks or 20 sessions, whichever comes first

Other: Yoga Therapy (YT)

Interventions

Yoga Therapy (YT) is an evidence-based mind-body practice recommended for cancer to relieve nausea, fatigue, pain, sleep disruption, psychosocial distress, musculoskeletal symptoms, and cognitive dysfunction, all common symptoms experienced during HSCT.

SC: Enhanced Stand of Care GroupYT: Yoga Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male and female cancer patients
  • Age 18 or older
  • Understand and read English
  • Scheduled to undergo their first autologous or allogeneic HSCT (even number of each) at MDA with a minimum of 2-week inpatient hospital stay
  • Be willing to follow protocol requirements
  • Sign a written informed consent

You may not qualify if:

  • Have extreme mobility issues that preclude participating in the Yoga program
  • Have major thought disorders such as schizophrenia or uncontrolled bipolar disorder
  • Have hematopoietic cell transplantation HCT comorbidity score of 3 or higher (excluding cancer)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UT MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Conditions

Neoplasms

Interventions

Yoga

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesExercise Movement TechniquesPhysical Therapy Modalities

Study Officials

  • Lorenzo Cohen, PHD

    UT MD Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Lorenzo Cohen, PHD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 17, 2026

First Posted

August 20, 2026

Study Start (Estimated)

February 1, 2027

Primary Completion (Estimated)

April 13, 2030

Study Completion (Estimated)

April 13, 2032

Last Updated

August 20, 2026

Record last verified: 2026-08

Locations