Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers

NCT07764809 | Not Yet Recruiting

• 1 other identifier: IAS-SKIN-2026-002
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry. Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.

Conditions

Skin Diseases; Photoaging; Skin Hydration

Keywords

skin hydration; UVA exposure; driving; photoaging; bioimpedance; facial asymmetry; Florida; BT-Analyze

Outcome Measures

Primary Outcomes (1)

• Hydration Asymmetry Index (HAI)

  Difference in mean BT-Analyze bioimpedance scores between the right and left cheeks (HAI = right cheek mean minus left cheek mean). A positive value indicates lower hydration on the left cheek relative to the right.

  Single visit (Day 1)

Secondary Outcomes (4)

• Correlation between cumulative driving exposure and HAI

  Single visit (Day 1)

• HAI by window tinting status

  Single visit (Day 1)

• HAI by sunscreen application habit

  Single visit (Day 1)

• Forehead hydration as symmetry reference

  Single visit (Day 1)

Study Arms (1)

Female Florida Drivers

Female drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window.

Other: BT-Analyze bioimpedance skin hydration measurement

Interventions

BT-Analyze bioimpedance skin hydration measurement OTHER

Non-invasive skin hydration measurement at three facial zones (right cheek, left cheek, forehead) using the BT-Analyze bioimpedance device. Three measurements per zone. Single visit.

Female Florida Drivers

Eligibility Criteria

• Age: 25 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Convenience sample of female drivers aged 25-65 years residing in Florida, recruited from an esthetics practice client base and referral networks in the Orlando metropolitan area.

You may qualify if:

• Female sex, aged 25 to 65 years (inclusive)
• Valid driver's license and active driving for a minimum of 3 years
• Driving frequency of at least 3 days per week on average
• Florida residency for a minimum of 2 years prior to enrollment
• Ability to provide written informed consent in English or Russian

You may not qualify if:

• Window tinting on the driver-side window of the participant's primary vehicle
• Regular sunscreen application specifically to the left side of the face before driving (more than half of driving occasions in the past month)
• Active skin disease on the face at time of assessment
• Injectable cosmetic procedures (Botox or fillers) in the past 6 months
• Laser resurfacing or chemical peel in the past 3 months
• Inability to refrain from facial cosmetics for at least 2 hours prior to the visit

Sponsors & Collaborators

• IAS Skin Care: lead

Study Sites (1)

IAS Skin Care

Orlando, Florida, 32835, United States

Location

MeSH Terms

Conditions

Skin Diseases; Facial Asymmetry

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Olga IAS, M.Sc

CONTACT

689-249-26-77; ias.skincare1@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: INDUSTRY
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Licensed Esthetician, M.Sc.

Study Record Dates

• First Submitted: August 10, 2026
• First Posted: August 14, 2026
• Study Start (Estimated): October 1, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: August 14, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)