Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Gynecologic Surgery

NCT07764276 | Recruiting

• 1 other identifier: 202402107RINC
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Enhanced Recovery After Surgery (ERAS) is a multidisciplinary perioperative care program designed to reduce surgical stress, accelerate postoperative recovery, and improve clinical outcomes. This prospective, non-randomized study aims to evaluate the effectiveness of an ERAS program in patients undergoing gynecologic surgery at National Taiwan University Hospital Hsin-Chu Branch. Patients who choose to participate in the ERAS program will receive perioperative care according to the institutional ERAS protocol, while those who choose conventional perioperative care will serve as the comparison group. Perioperative outcomes, postoperative recovery, postoperative complications, pain scores, and other clinical outcomes will be compared between the two groups to evaluate the clinical impact of implementing an ERAS program.

Conditions

ERAS; Gynecologic Surgery; Gynecologic Oncological Pelvic/Abdominal Surgery

Outcome Measures

Primary Outcomes (2)

• Time to First Ambulation

  Time from return to the hospital ward after surgery to the first ambulation, defined as leaving the bed and standing independently.

  Up to 3 days after surgery

• Postoperative Pain Score

  Postoperative pain intensity will be assessed using the Numerical Rating Scale (NRS), ranging from 0 to 10, with 0 indicating no pain and 10 indicating the worst possible pain. Higher scores indicate greater pain intensity.

  4, 8, 16, 24, 48 hours after surgery

Secondary Outcomes (6)

• Time to First Gas Passage

  Up to 7 days after surgery

• Time to First Stool Passage

  Up to 7 days after surgery

• Time to removal of Foley catheter

  Up to 7 days after surgery

• Postoperative nausea or vomiting

  Up to 7 days after surgery

• Overall Postoperative Complication Rate

  Up to 90 days after surgery

Study Arms (2)

Enhanced Recovery After Surgery (ERAS)

EXPERIMENTAL

Participants receive perioperative care according to the institutional ERAS protocol, including preoperative education, preoperative carbohydrate intake, optimized anesthesia, multimodal analgesia, early oral feeding, early mobilization, and other evidence-based perioperative care measures.

Other: Enhanced Recovery After Surgery (ERAS)

Conventional Perioperative Care

ACTIVE COMPARATOR

Participants receive conventional perioperative care according to routine institutional practice without implementation of the ERAS protocol.

Other: Conventional Perioperative Care

Interventions

Enhanced Recovery After Surgery (ERAS) OTHER

A multidisciplinary perioperative care program designed to reduce surgical stress and enhance postoperative recovery.

Enhanced Recovery After Surgery (ERAS)

Conventional Perioperative Care OTHER

Standard perioperative care according to routine institutional practice.

Conventional Perioperative Care

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female scheduled for laparotomic gynecologic surgery (including hysterectomy, myomectomy, adenomyomectomy, oophorectomy or oophrocystectomy, staging surgery, debulking surgery or interval debulking surgery)
• years old or older
• American Society of Anesthesiologists Physical Status classification I to III.

You may not qualify if:

• Female undergo laparoscopic surgery but are converted to laparotomic surgery
• History of delayed gastric emptying, gastrointestinal motility disorders or chronic pain
• Female undergo emergent surgery.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital Hsin-Chu Branch

Hsinchu, Taiwan

RECRUITING

MeSH Terms

Interventions

Enhanced Recovery After Surgery

Intervention Hierarchy (Ancestors)

Perioperative Care; Surgical Procedures, Operative

Study Officials

• Chia-Yi Lee, MD

  National Taiwan University Hospital Hsin-Chu Branch

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Chia-Yi Lee, MD

CONTACT

+886-972652431; plzfixthecar@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 4, 2026
• First Posted: August 13, 2026
• Study Start: May 16, 2024
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2027
• Last Updated: August 13, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)