NCT07763314

Brief Summary

The incidence of early-onset colorectal cancer (EOCRC; patients younger than 50 years) has increased worldwide over recent decades. This study aimed to provide nationwide evidence on surgically treated EOCRC in Switzerland.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
73,771

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2003

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2003

Completed
20 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2023

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

August 10, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 13, 2026

Completed
Last Updated

August 13, 2026

Status Verified

August 1, 2026

Enrollment Period

20 years

First QC Date

August 10, 2026

Last Update Submit

August 10, 2026

Conditions

Colorectal Cancer (CRC)Early Onset Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

  • Incidence

    2003 - 2022

Secondary Outcomes (4)

  • Localization

    2003 - 2022

  • Sociodemographic trends

    2003 - 2022

  • Mortality

    Periprocedural

  • Length of hospital stay

    Periprocedural

Study Arms (2)

Early-onset colorectal cancer

Colorectal cancer in adults younger than 50 years

Procedure: Early-onset colorectal cancer resection

Late-onset colorectal cancer

Colorectal cancer in adults older than 50 years

Procedure: Late-onset colorectal cancer resection

Interventions

Early-onset colorectal cancer resectionPROCEDURE

Any kind of surgical early-onset colorectal cancer resection

Early-onset colorectal cancer
Late-onset colorectal cancer resectionPROCEDURE

Any kind of surgical late-onset colorectal cancer resection

Late-onset colorectal cancer

Eligibility Criteria

Age15 Years+
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with colorectal cancer resection in Switzerland between 2003 and 2022.

You may qualify if:

  • \- All patients with colorectal cancer resection in Switzerland between 2003 and 2022.

You may not qualify if:

  • incomplete case documentation
  • age under 15 years
  • other hospitals than general or surgical hospitals
  • no index operation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HOCH Health Ostschweiz, Kantonsspital St.Gallen

Sankt Gallen, St.Gallen, 9000, Switzerland

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
90 Days
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 10, 2026

First Posted

August 13, 2026

Study Start

January 1, 2003

Primary Completion

December 31, 2022

Study Completion

March 1, 2023

Last Updated

August 13, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Locations

CH(1)