Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

2.1%

2 terminated out of 97 trials

Success Rate

88.2%

+1.7% vs benchmark

Late-Stage Pipeline

4%

4 trials in Phase 3/4

Results Transparency

27%

4 of 15 completed with results

Key Signals

4 with results88% success

Data Visualizations

Phase Distribution

71Total
Not Applicable (17)
Early P 1 (1)
P 1 (31)
P 2 (18)
P 3 (3)
P 4 (1)

Trial Status

Recruiting49
Not Yet Recruiting19
Completed15
Active Not Recruiting6
Enrolling By Invitation3
Unknown3

Trial Success Rate

88.2%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (97)

Showing 20 of 20 trials
NCT07448142Phase 2RecruitingPrimary

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

NCT04083599Phase 1Active Not Recruiting

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

NCT07397338Phase 1Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

NCT07562659Phase 2Recruiting

Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer

NCT05198934Phase 3CompletedPrimary

Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation

NCT07542704Phase 1Not Yet Recruiting

A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies

NCT07523763Phase 2Active Not Recruiting

Neoadjuvant Low-dose Immunotherapy in Locally Advanced MMR-deficient Colorectal Cancer

NCT06026410Phase 1Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

NCT07223047Phase 1Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

NCT05462717Phase 1Active Not Recruiting

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

NCT07011576Phase 2Recruiting

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)

NCT06599502Phase 1Terminated

A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation

NCT05176483Phase 1Recruiting

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

NCT07463599Phase 1Recruiting

Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

NCT07435038Phase 1Not Yet Recruiting

Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

NCT06895031Phase 2Recruiting

Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

NCT07321106Phase 1Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

NCT07423130CompletedPrimary

Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery

NCT07405736Phase 2Not Yet Recruiting

Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer

NCT07349537Phase 1Recruiting

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

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