NCT07760753

Brief Summary

This study examines how body water distribution changes with age. Using a non-invasive body composition device (bioelectrical impedance analysis), researchers measured the amount of water inside and outside the body's cells, both for the whole body and separately for the arms, trunk, and legs, in adults aged 18 to 83. The study explores whether the balance between water inside and outside cells shifts as people get older, independent of their body weight, and whether this pattern differs between men and women or between different parts of the body.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
568

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
8.7 years until next milestone

First Submitted

Initial submission to the registry

August 7, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 12, 2026

Completed
Last Updated

August 12, 2026

Status Verified

August 1, 2026

Enrollment Period

4.9 years

First QC Date

August 7, 2026

Last Update Submit

August 7, 2026

Conditions

Body WaterAging

Keywords

bioelectrical impedance analysisextracellular waterintracellular waterECW/TBW ratiosegmental body compositioncellular hydration

Outcome Measures

Primary Outcomes (1)

  • Whole-Body ECW/TBW Ratio in Relation to Age

    The extracellular-to-total body water ratio (ECW/TBW), a marker of cellular hydration status, was measured for the whole body using bioelectrical impedance analysis (InBody S10). Values were correlated with participant age, both unadjusted and adjusted for body mass index, to assess whether cellular hydration status changes with age independently of body mass.

    At enrollment

Secondary Outcomes (9)

  • Segmental ECW/TBW Ratio in Relation to Age

    At enrollment

  • Right-Left Difference in Segmental Water Content

    At enrollment

  • Right-Left Difference in Segmental Lean Mass

    At enrollment

  • Whole-Body Intracellular Water (ICW) in Relation to Age and Body Weight

    At enrollment

  • Whole-Body Extracellular Water (ECW) in Relation to Age and Body Weight

    At enrollment

  • +4 more secondary outcomes

Other Outcomes (4)

  • Proportion of Participants Outside Reference Range for ICW

    At enrollment

  • Proportion of Participants Outside Reference Range for ECW

    At enrollment

  • Proportion of Participants Outside Reference Range for TBW

    At enrollment

  • +1 more other outcomes

Study Arms (1)

Adults undergoing bioimpedance body composition analysis

Adult participants aged 18-83 years who underwent whole-body and segmental bioelectrical impedance analysis (InBody S10) as part of a single, non-interventional assessment of body water distribution.

Eligibility Criteria

Age18 Years - 83 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Volunteers recruited between the beginning of 2013 and the end of 2017 from among students and employees of the Medical University of Silesia (Katowice, Poland), and their families and friends.

You may qualify if:

  • Adults aged 18 years or older
  • Completion of the study participation agreement (informed consent)
  • General good health

You may not qualify if:

  • Pregnancy
  • Presence of a cardiac pacemaker or other implanted electronic medical device
  • Presence of metal implants contraindicating bioelectrical impedance analysis
  • Inability to stand or maintain the position required for measurement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland

Sosnowiec, 41--200, Poland

Location

Related Publications (1)

  • Lebiedowska A, Hartman-Petrycka M, Blonska-Fajfrowska B. How reliable is BMI? Bioimpedance analysis of body composition in underweight, normal weight, overweight, and obese women. Ir J Med Sci. 2021 Aug;190(3):993-998. doi: 10.1007/s11845-020-02403-3. Epub 2020 Oct 21.

    PMID: 33083960RESULT

Study Officials

  • Barbara Błońska-Fajfrowska, Prof

    Medical University of Silesia, Katowice, Poland

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 7, 2026

First Posted

August 12, 2026

Study Start

January 1, 2013

Primary Completion

December 1, 2017

Study Completion

December 1, 2017

Last Updated

August 12, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Data sharing was not part of the original study protocol, which began enrollment in 2013, predating the ICMJE requirement for data sharing statements (applicable to trials enrolling participants from January 1, 2019 onward). The dataset has been and will continue to be used by the same research team for related analyses reported in separate publications. De-identified data may be made available from the corresponding author upon reasonable request.

Locations

PL(1)