A Clinical Trial to Evaluate the Effects of a Supplement on Cognitive Function and Energy Levels

NCT07755475 | Completed

• 2 other identifiers: 20772legacy-20772
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the effects of Artah's Cellular Hydration electrolyte supplement on cognitive function and energy levels in healthy adults aged 25-60 who experience mild to moderate fatigue, brain fog, or related symptoms. The trial is a single-arm, unblinded, virtual study in which all 50 participants will use the test product daily for 4 weeks. Participants will complete self-reported questionnaires at Baseline, Week 1, Week 2, Week 3, and Week 4, and will undergo cognitive battery testing at Baseline and Week 4. The primary endpoint is change in cognitive performance scores as measured by a standardized cognitive battery. Secondary endpoints include participants' self-reported perceptions of mental clarity, alertness, mood, physical performance, overall energy levels, and frequency of food cravings.

Conditions

Cognitive Function; Fatigue; Energy Levels; Mental Clarity; Brain Fog; Food Cravings

Outcome Measures

Primary Outcomes (6)

• Change in Cognitive Battery Test Score (Polygons)

  Change in processing speed and information sorting ability assessed via the Polygons timed cognitive battery subtest

  Baseline and Week 4

• Change in Cognitive Battery Test Score (Double Trouble)

  Change in selective attention and processing speed assessed via the Double Trouble timed cognitive battery subtest (Stroop-based)

  Baseline and Week 4

• Change in Cognitive Battery Test Score (Feature Match)

  Change in focus and processing speed assessed via the Feature Match timed cognitive battery subtest

  Baseline and Week 4

• Change in Cognitive Battery Test Score (Paired Associates)

  Change in memory recall assessed via the Paired Associates performance-based cognitive battery subtest

  Baseline and Week 4

• Change in Cognitive Battery Test Score (Digit Span)

  Change in short-term memory and cognitive flexibility assessed via the Digit Span performance-based cognitive battery subtest

  Baseline and Week 4

• Change in Cognitive Battery Test Score (Spatial Planning)

  Change in executive function and logical decision-making assessed via the Spatial Planning timed cognitive battery subtest

  Baseline and Week 4

Secondary Outcomes (6)

• Change in Self-Reported Mental Clarity and Focus

  Baseline, Week 1, Week 2, Week 3, and Week 4

• Change in Self-Reported Alertness

  Baseline, Week 1, Week 2, Week 3, and Week 4

• Change in Self-Reported Mood

  Baseline, Week 1, Week 2, Week 3, and Week 4

• Change in Self-Reported Physical Performance

  Baseline, Week 1, Week 2, Week 3, and Week 4

• Change in Self-Reported Overall Energy Levels

  Baseline, Week 1, Week 2, Week 3, and Week 4

Study Arms (1)

Cellular Hydration Supplement

ACTIVE COMPARATOR

Dietary Supplement: Cellular Hydration Supplement

Interventions

Cellular Hydration Supplement DIETARY_SUPPLEMENT

All 50 participants receive the Artah Cellular Hydration electrolyte supplement taken twice daily (once in the morning before the first meal and once in the afternoon after lunch or before evening exercise) as one teaspoon (approximately 7 g) stirred into 750 ml of water for 4 weeks.

Cellular Hydration Supplement

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Be male or female.
• Be aged 25-60.
• Anyone currently experiencing mild to moderate issues with at least three of the following: low energy or fatigue
• difficulty concentrating or low mental sharpness
• experiences of brain fog or lack of mental clarity
• feeling of low productivity
• muscle weakness
• unwanted food cravings.
• Undertakes moderate to high-intensity exercise such as jogging/running and/or heavy resistance training at least three times per week.
• Willing to refrain from taking any products, medications, or supplements that target energy, cognition, or physical performance during the test period.
• Anyone with a BMI 18.5 to 30.
• Anyone who has access to a device (e.g., smartphone, laptop, computer) for reliable internet.
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
• Anyone willing to maintain a consistent diet and physical activity throughout study duration.

You may not qualify if:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.
• Anyone suffering from gastrointestinal disorders including but not limited to small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and celiac disease.
• Anyone suffering from hyperkalemia (high potassium), liver disease, or kidney disease.
• Anyone taking ACE inhibitors or potassium-sparing diuretics, examples include: Spironolactone (Aldactone), Eplerenone (Inspra), Amiloride (Midamor), Triamterene (Maxzide), Lisinopril (Zestril, Prinivil), Enalapril (Vasotec), Ramipril (Altace), Benazepril (Lotensin), Quinapril (Accupril), Losartan (Cozaar), Valsartan (Diovan), Olmesartan (Benicar), Irbesartan (Avapro), Lithium carbonate (Lithobid, Eskalith).
• Anyone taking antibiotics.
• Anyone with any allergies or sensitivities to any of the study product ingredients.
• Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
• Anyone unwilling to follow the study protocol.
• Anyone with a history of substance abuse.
• Anyone who is a shift worker with an irregular sleep-wake cycle.
• Anyone who drinks heavily (8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men).
• Anyone who is currently a smoker or has been a smoker in the past 3 months.
• Currently partaking in another research study, or planning to at any point during this study's duration.

Sponsors & Collaborators

• Artah Nutrition Limited: lead
• Citruslabs: collaborator

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89101, United States

Location

MeSH Terms

Conditions

Fatigue; Mental Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 5, 2026
• First Posted: August 10, 2026
• Study Start: June 13, 2025
• Primary Completion: August 16, 2025
• Study Completion: August 16, 2025
• Last Updated: August 10, 2026

Record last verified: 2026-08

Locations

US (1)