A Clinical Trial to Evaluate the Effects of a Supplement on Cognitive Performance

NCT07742605 | Completed

• 2 other identifiers: 20789legacy-20789
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the effects of the Xula Herbs Mind Food supplement on cognitive performance in adults aged 25-70 who report difficulty concentrating, memory challenges, brain fog, and low productivity. The trial is a single-arm, open-label, virtual study conducted over 6 weeks in 35 participants. Participants will use the test product three times daily (sprayed three times under the tongue, at least 30 minutes before a meal, and not after 6 pm) for the duration of the study. Cognitive performance will be assessed via a Cognitive Battery Test at Baseline and Week 6, and self-reported questionnaires will be completed at Baseline, Week 2, Week 4, and Week 6.

Conditions

Cognitive Impairment; Brain Fog; Cognitive Performance; Memory Difficulties; Difficulty Concentrating; Mental Clarity

Outcome Measures

Primary Outcomes (6)

• Change in Cognitive Battery Test Score (Polygons)

  Change in performance on the Polygons timed processing test, measuring the brain's ability to sort and clarify information and judge the correct response, assessed via the Cognitive Battery Test

  Baseline and Week 6

• Change in Cognitive Battery Test Score (Double Trouble)

  Change in performance on the Double Trouble timed test, measuring selective attention and processing speed based on the Stroop paradigm, assessed via the Cognitive Battery Test

  Baseline and Week 6

• Change in Cognitive Battery Test Score (Feature Match)

  Change in performance on the Feature Match timed focus and processing task, assessed via the Cognitive Battery Test

  Baseline and Week 6

• Change in Cognitive Battery Test Score (Paired Associates)

  Change in performance on the Paired Associates memory task, measuring recall of sequences and locations of items in increasing quantity, assessed via the Cognitive Battery Test

  Baseline and Week 6

• Change in Cognitive Battery Test Score (Digit Span)

  Change in performance on the Digit Span task, measuring short-term memory and attention by recalling displayed number sequences of increasing length, assessed via the Cognitive Battery Test

  Baseline and Week 6

• Change in Cognitive Battery Test Score (Spatial Planning)

  Change in performance on the Spatial Planning timed task, measuring executive function and ability to reorganize numbers into correct order, assessed via the Cognitive Battery Test

  Baseline and Week 6

Secondary Outcomes (6)

• Change in Self-Reported Mental Clarity

  Baseline, Week 2, Week 4, and Week 6

• Change in Self-Reported Focus

  Baseline, Week 2, Week 4, and Week 6

• Change in Self-Reported Memory Function

  Baseline, Week 2, Week 4, and Week 6

• Change in Self-Reported Alertness

  Baseline, Week 2, Week 4, and Week 6

• Change in Self-Reported Mood

  Baseline, Week 2, Week 4, and Week 6

Study Arms (1)

Xula Herbs Mind Food Supplement

EXPERIMENTAL

Dietary Supplement: Xula Herbs Mind Food Supplement

Interventions

Xula Herbs Mind Food Supplement DIETARY_SUPPLEMENT

All 35 participants receive the Xula Herbs Mind Food supplement taken three times daily by spraying three times under the tongue, at least 30 minutes before a meal and not after 6 pm, for 6 weeks

Xula Herbs Mind Food Supplement

Eligibility Criteria

• Age: 25 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Be male or female.
• Be aged 25-70.
• Anyone experiencing issues with all of the following over the past four weeks: difficulty concentrating or low mental sharpness
• difficulty with memory
• experiences of brain fog or lack of mental clarity
• feeling of low productivity.
• Willing to refrain from taking any new products, over-the-counter medications, or supplements that may affect cognitive ability during the test period.
• If taking any products, over-the-counter medications, or supplements that may affect cognitive ability, has been doing so consistently for at least three months and is willing to maintain this routine for the duration of the study.
• Anyone who is generally healthy - does not live with any uncontrolled chronic disease.

You may not qualify if:

• Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.
• Anyone with any allergies or sensitivities to any of the study product ingredients.
• Anyone who is pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
• Anyone unwilling to follow the study protocol.
• Anyone diagnosed with a neurodegenerative condition.
• Anyone taking an anticoagulant (also commonly referred to as a blood thinner) prescription medication.
• Anyone with liver disease or kidney disease.
• Anyone taking hormonal birth control or contraceptives.
• Anyone with a history of substance abuse.
• Anyone who drinks heavily (8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men).
• Currently partaking in another research study or will be partaking in any other research study at any point during this study's duration.

Sponsors & Collaborators

• Citruslabs: collaborator
• Xula Wellness LLC: lead

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89118, United States

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Mental Fatigue

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Fatigue; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2026
• First Posted: August 3, 2026
• Study Start: July 11, 2025
• Primary Completion: September 30, 2025
• Study Completion: September 30, 2025
• Last Updated: August 3, 2026

Record last verified: 2026-07

Locations

US (1)