A Clinical Trial to Investigate the Efficacy of the Brain Blossom Supplement to Improve Cognitive Function and Memory

NCT07564804 | Completed

• 1 other identifier: 20737
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the efficacy of BioNatureHealth's Brain Blossom supplement in improving cognitive function and memory in adults aged 50-70 years. Participants will be randomized to receive either the test product or placebo over 8 weeks, with cognitive battery testing and questionnaires administered at multiple timepoints.

Conditions

Cognitive Function; Memory; Cognitive Decline

Keywords

Brain health; Dietary supplement

Outcome Measures

Primary Outcomes (1)

• Change in Cognitive Battery Composite Score

  Cognitive function and memory will be assessed using a cognitive battery consisting of Polygons, Double Trouble, Feature Match, Paired Associates, Digit Span, and Spatial Planning tasks.

  Baseline, Week 2, Week 4, Week 6, Week 8

Secondary Outcomes (5)

• Change in Self-Reported Memory and Recall

  Baseline, Week 2, Week 4, Week 6, Week 8

• Change in Self-Reported Focus and Attentiveness

  Baseline, Week 2, Week 4, Week 6, Week 8

• Change in Self-Reported Comprehension

  Baseline, Week 2, Week 4, Week 6, Week 8

• Change in Self-Reported Mental Clarity

  Baseline, Week 2, Week 4, Week 6, Week 8

• Change in Self-Reported Learning Acuity

  Baseline, Week 2, Week 4, Week 6, Week 8

Study Arms (2)

Brain Blossom Supplement

EXPERIMENTAL

Participants receive the Brain Blossom supplement daily for 8 weeks.

Dietary Supplement: Dietary Supplement: Brain Blossom

Placebo

PLACEBO COMPARATOR

Participants receive placebo capsules daily for 8 weeks.

Dietary Supplement: Placebo

Interventions

Dietary Supplement: Brain Blossom DIETARY_SUPPLEMENT

Six capsules taken once daily in the morning with water.

Brain Blossom Supplement

Placebo DIETARY_SUPPLEMENT

Rice flour capsules

Placebo

Eligibility Criteria

• Age: 50 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female
• Aged 50-70 years
• Seeking to support cognitive function and memory
• Experiences at least three symptoms related to cognitive decline
• Willing to avoid new cognitive-related medications/supplements
• Generally healthy

You may not qualify if:

• Medical conditions affecting cognition
• Psychiatric or neurological disorders
• Diabetes or heart conditions
• Use of anticoagulants, benzodiazepines, or pain medications
• Substance abuse or heavy alcohol use
• Allergies to product ingredients
• Inability to comply with protocol

Sponsors & Collaborators

• Bio Nature Health: lead
• Citruslabs: collaborator

Study Sites (1)

Citruslabs

Las Vegas, Nevada, 89118, United States

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 27, 2026
• First Posted: May 4, 2026
• Study Start: March 28, 2025
• Primary Completion: June 27, 2025
• Study Completion: June 27, 2025
• Last Updated: May 4, 2026

Record last verified: 2026-04

Locations

US (1)