Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy in Stroke

NCT07725003 | Recruiting DMC

• 1 other identifier: REC/RCR & AHS/25/0201
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients.

Conditions

Stroke

Keywords

Balance Disorders; Motor Relearning Program; Stroke Telerehabilitation

Outcome Measures

Primary Outcomes (2)

• Fugl-Meyer Assessment (FMA) Motor Function Score

  Change in motor function will be assessed using the Fugl-Meyer Assessment (FMA). The FMA evaluates motor recovery of the upper and lower extremities, with higher scores indicating better motor function.

  Baseline and after 6 weeks of intervention

• Berg Balance Scale (BBS) Score

  Balance performance will be assessed using the Berg Balance Scale (BBS). The scale consists of 14 functional balance tasks, with higher scores indicating better balance.

  Baseline and after 6 weeks of intervention

Secondary Outcomes (1)

• Timed Up and Go (TUG) Test

  Baseline and after 6 weeks of intervention

Study Arms (2)

Telerehabilitation-Based Motor Relearning Program (MRP)

EXPERIMENTAL

Participants in this arm will receive a structured Motor Relearning Program delivered through telerehabilitation via secure video conferencing. The intervention will consist of task-specific, goal-oriented exercises focusing on trunk control, balance, functional transfers, gait training, and coordination. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist.

Other: Telerehabilitation Based Motor Relearning Program

Telerehabilitation-Based Conventional Physical Therapy

EXPERIMENTAL

Participants in this arm will receive conventional physical therapy delivered through telerehabilitation via secure video conferencing. The intervention will include range-of-motion exercises, stretching, strengthening, balance training, gait exercises, and functional mobility activities. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist.

Other: Conventional physical therapy

Interventions

Conventional physical therapy OTHER

Participants will receive conventional physiotherapy through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, exercise session, and cool-down. The program consists of active-assisted and active range-of-motion exercises, stretching, breathing exercises, strengthening exercises, weight-shifting activities, marching in place, gait training, dynamic mobility exercises, and light resistance exercises using Theraband where appropriate. Exercise intensity will be moderate and adjusted according to each participant's tolerance and clinical progress.

Also known as: Standard physical therapy

Telerehabilitation-Based Conventional Physical Therapy

Telerehabilitation Based Motor Relearning Program OTHER

Participants will receive a Motor Relearning Program (MRP) delivered through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, task-specific functional training, and cool-down. Exercises include sitting and standing balance training, trunk control, sit-to-stand practice, upper limb reaching, trunk rotation, weight-shifting, step training, walking practice, stair simulation, obstacle negotiation, dual-task activities, community mobility simulation, and functional transfer training. Exercise intensity will be moderate and progressively increased according to the participant's tolerance and functional performance.

Also known as: MRP, Tas-Specific Motor Relearning, Telerehabilitation MRP

Telerehabilitation-Based Motor Relearning Program (MRP)

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or female participants.
• Diagnosed with ischemic or hemorrhagic stroke 3-12 months prior to enrollment.
• Medically stable and cleared to participate in physical rehabilitation.
• Mini-Mental State Examination (MMSE) score ≥24.
• Able to understand and follow verbal instructions.
• Have access to a smartphone, tablet, or computer with a stable internet connection for telerehabilitation sessions.
• Willing and able to provide written informed consent.

You may not qualify if:

• Presence of other neurological disorders (e.g., Parkinson's disease or multiple sclerosis).
• Uncontrolled hypertension or recent cardiac event.
• Severe visual, auditory, or communication impairments that prevent participation.
• Currently enrolled in another structured rehabilitation program.
• Any musculoskeletal or medical condition that would interfere with safe participation in the intervention.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Aziz Fatimah Hospital

Faisalabad, Punjab Province, 38000, Pakistan

RECRUITING

Related Publications (8)

• Winstein CJ, Stein J, Arena R, Bates B, Cherney LR, Cramer SC, Deruyter F, Eng JJ, Fisher B, Harvey RL, Lang CE, MacKay-Lyons M, Ottenbacher KJ, Pugh S, Reeves MJ, Richards LG, Stiers W, Zorowitz RD; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Quality of Care and Outcomes Research. Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2016 Jun;47(6):e98-e169. doi: 10.1161/STR.0000000000000098. Epub 2016 May 4.

  PMID: 27145936 BACKGROUND

• Ghrouz A, Marco E, Munoz-Redondo E, Boza R, Ramirez-Fuentes C, Duarte E. The effect of motor relearning on balance, mobility and performance of activities of daily living among post-stroke patients: Study protocol for a randomised controlled trial. Eur Stroke J. 2022 Mar;7(1):76-84. doi: 10.1177/23969873211061027. Epub 2022 Feb 11.

  PMID: 35300258 BACKGROUND

• Khallaf ME. Effect of Task-Specific Training on Trunk Control and Balance in Patients with Subacute Stroke. Neurol Res Int. 2020 Nov 17;2020:5090193. doi: 10.1155/2020/5090193. eCollection 2020.

  PMID: 33294224 BACKGROUND

• Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC. Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.09.014. Epub 2015 Oct 23.

  PMID: 26483155 BACKGROUND

• Cramer SC, Dodakian L, Le V, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, Putrino D, Agrawal K, Ngo K, Roth EJ, Tirschwell DL, Woodbury ML, Zafonte R, Zhao W, Spilker J, Wolf SL, Broderick JP, Janis S; National Institutes of Health StrokeNet Telerehab Investigators. Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke: A Randomized Clinical Trial. JAMA Neurol. 2019 Sep 1;76(9):1079-1087. doi: 10.1001/jamaneurol.2019.1604.

  PMID: 31233135 BACKGROUND

• Laver KE, Adey-Wakeling Z, Crotty M, Lannin NA, George S, Sherrington C. Telerehabilitation services for stroke. Cochrane Database Syst Rev. 2020 Jan 31;1(1):CD010255. doi: 10.1002/14651858.CD010255.pub3.

  PMID: 32002991 BACKGROUND

• Alwadai B, Lazem H, Almoajil H, Hall AJ, Mansoubi M, Dawes H. Telerehabilitation and Its Impact Following Stroke: An Umbrella Review of Systematic Reviews. J Clin Med. 2024 Dec 26;14(1):50. doi: 10.3390/jcm14010050.

  PMID: 39797132 BACKGROUND

• Feigin VL, Brainin M, Norrving B, Martins S, Sacco RL, Hacke W, Fisher M, Pandian J, Lindsay P. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917.

  PMID: 34986727 BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Misbah Waris, phd

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Imran Amjad, phd

CONTACT

+923324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Blinding
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 21, 2026
• First Posted: July 24, 2026
• Study Start: June 5, 2025
• Primary Completion (Estimated): August 6, 2026
• Study Completion (Estimated): August 6, 2026
• Last Updated: July 24, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)