NCT07720141

Brief Summary

The goal of this research study is to compare two different ways to increase lung cancer screening rates for tobacco quitline clients.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
650

participants targeted

Target at P75+ for not_applicable lung-cancer

Timeline
91mo left

Started Jan 2027

Longer than P75 for not_applicable lung-cancer

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 17, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 22, 2026

Completed
5 months until next milestone

Study Start

First participant enrolled

January 1, 2027

Expected
5.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2032

2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2034

Last Updated

July 22, 2026

Status Verified

July 1, 2026

Enrollment Period

5.5 years

First QC Date

July 17, 2026

Last Update Submit

July 17, 2026

Conditions

Keywords

Tobacco

Outcome Measures

Primary Outcomes (1)

  • Safety and Adverse Events (AEs)

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 6.0

    Through study completion; an average of 1 year

Study Arms (2)

CMP: Comparator - Low-Touch Strategy (Usual Practice): LCS Educational Resources

EXPERIMENTAL

Investigators will use a parallel randomized controlled trial to compare a high-touch strategy (emailing/texting + decision coaching + navigation) to a low-touch strategy (emailing/texting) to distribute evidence based LCS educational resources to increase awareness and demand for LCS among quitline clients.

Behavioral: High-touch strategy

INT: Intervention - High-Touch Strategy: LCS Educational Resources, Decision Coaching, Navigation

EXPERIMENTAL

Investigators will use a parallel randomized controlled trial to compare a high-touch strategy (emailing/texting + decision coaching + navigation) to a low-touch strategy (emailing/texting) to distribute evidence based LCS educational resources to increase awareness and demand for LCS among quitline clients.

Behavioral: High-touch strategy

Interventions

Participants will receive the LCS educational materials, decision coaching call for the SDM visit, and navigation for LCS.

CMP: Comparator - Low-Touch Strategy (Usual Practice): LCS Educational ResourcesINT: Intervention - High-Touch Strategy: LCS Educational Resources, Decision Coaching, Navigation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Quitline Client
  • Quitline client participants must meet the criteria for LCS with regards to age (50 to 80 years) and smoking history (20+ pack-years). This project will not re-confirm quitline client participant eligibility for screening. Tobacco treatment specialists will elicit study interest from only eligible quitline clients.
  • Representative of the Quitline Community
  • Representative of the Quitline Community will include any employee of the quitline service provider, representative from an organization that collaborates or funds a tobacco quitline, and/or a representative of the state department of health. All individuals will be adults (18 years and older) and able to speak English.
  • Representative of the Healthcare Sector
  • Representative of the healthcare sector will include any adult who works in healthcare, including but not limited to physicians, healthcare administrative leaders/managers, nurses, advanced practice providers. All individuals will be adults (18 years and older) and able to speak English.

You may not qualify if:

  • Not applicable as our focus on quitline clients and representatives (adults) of the quitline community or the healthcare sector.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UT MD Anderson

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Lisa Lowenstein, PHD

    UT MD Anderson

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 17, 2026

First Posted

July 22, 2026

Study Start (Estimated)

January 1, 2027

Primary Completion (Estimated)

June 30, 2032

Study Completion (Estimated)

June 30, 2034

Last Updated

July 22, 2026

Record last verified: 2026-07

Locations