Population Health Management -Increase Lung Cancer Screening in Community Health Centers (LungSMART)

NCT07599943 | Not Yet Recruiting DMC

• 2 other identifiers: HCI1900121UG3CA287109-01
• Study Type: interventional
• Target: 18,894
• Locations: 1 country
• Sites: 1

Brief Summary

The long-term goal of LungSMART Utah is to increase the reach of Low-Dose Computed Tomography (LDCT) screening for lung cancer (hereafter referred to as Lung Cancer Screening or LCS) at scale in low-resource healthcare settings.

Conditions

Lung Cancer

Outcome Measures

Primary Outcomes (2)

• Stage 1: Completion of eligibility assessment

  To evaluate patient-level interventions with respect to increasing completed assessments in Stage 1. The outcome measure will report the proportion of participants who complete the LCS eligibility assessment.

  up to 18 weeks

• Stage 2: Completion of LCS

  To evaluate patient-level interventions with respect to increasing completed LCS in Stage 2. The outcome measure will report the proportion of participants who complete LCS.

  up to 30 weeks

Secondary Outcomes (7)

• Cost-effectiveness: Incremental Cost

  up to 30 weeks

• Cost-effectiveness: Incremental Effectiveness

  up to 30 weeks

• Proportion of patients who engage with interventions

  up to 18 weeks

• Proportion of patients who reply opting out of receiving interventions

  up to 30 weeks

• Proportion of patients who complete SDM

  up to 18 weeks

Other Outcomes (1)

• Baseline Characteristics that predict outcomes or moderate intervention effects

  up to 30 weeks

Study Arms (6)

Stage 1: Repeated Text Messages (TM+)

OTHER

Participants will receive up to nine text messages containing eligibility questions, along with up to nine reminder messages. If a participant successfully responds to the eligibility questions, no more messages will be sent. If a participant does not respond to the eligibility questions after receiving a text message, they will receive a reminder message three days later, prompting them to answer the questions.

Behavioral: Text Messages (TM+)

Stage 1: Repeated Text Messages and Chatbot (TM+/CA)

OTHER

Participants will receive up to nine text messages containing eligibility questions, along with up to nine reminder messages. If a participant successfully responds to the eligibility questions, no more messages will be sent. If a participant does not respond to the eligibility questions after receiving a text message, they will receive a reminder message three days later, prompting them to answer the questions. Participants will have access to a Lung Cancer Screening (LCS) Chatbot delivered via SMS.

Behavioral: Text Messages (TM+); Behavioral: Chatbot (CA)

Stage 1: Repeated Text Messages and Video (TM+/VID)

OTHER

Participants will receive up to nine text messages containing eligibility questions, along with up to nine reminder messages. If a participant successfully responds to the eligibility questions, no more messages will be sent. If a participant does not respond to the eligibility questions after receiving a text message, they will receive a reminder message three days later, prompting them to answer the questions. Participants can watch an educational video via SMS.

Behavioral: Text Messages (TM+); Behavioral: Video (VID)

Stage 1: Repeated Text Messages, Chatbot, and Video (TM+/CA/VID)

OTHER

Participants will receive up to nine text messages containing eligibility questions, along with up to nine reminder messages. If a participant successfully responds to the eligibility questions, no more messages will be sent. If a participant does not respond to the eligibility questions after receiving a text message, they will receive a reminder message three days later, prompting them to answer the questions. Participants will have access to a Lung Cancer Screening (LCS) Chatbot delivered via SMS. Participants can watch an educational video via SMS.

Behavioral: Text Messages (TM+); Behavioral: Chatbot (CA); Behavioral: Video (VID)

Stage 2: Chatbot and Reactive Patient Navigation (CA/RPN)

OTHER

RPN requires the participant to initiate the PN request. Participants receive up to three text messages scheduled four weeks apart.

Behavioral: Chatbot (CA); Behavioral: Reactive Patient Navigation (RPN)

Stage 2: Chatbot and Proactive Patient Navigation (CA/PPN)

OTHER

PPN does not require the participant to initiate the PN request and instead is a proactive call to the participant. Participants receive up to three text messages scheduled four weeks apart.

Behavioral: Chatbot (CA); Behavioral: Proactive Patient Navigation (PPN)

Interventions

Text Messages (TM+) BEHAVIORAL

A message informs the participants that an RN from the Hub will call them about SDM and LCS.

Stage 1: Repeated Text Messages (TM+); Stage 1: Repeated Text Messages and Chatbot (TM+/CA); Stage 1: Repeated Text Messages and Video (TM+/VID); Stage 1: Repeated Text Messages, Chatbot, and Video (TM+/CA/VID)

Chatbot (CA) BEHAVIORAL

Access to a chatbot for frequently asked questions about LCS

Also known as: Chatbot

Stage 1: Repeated Text Messages and Chatbot (TM+/CA); Stage 1: Repeated Text Messages, Chatbot, and Video (TM+/CA/VID); Stage 2: Chatbot and Proactive Patient Navigation (CA/PPN); Stage 2: Chatbot and Reactive Patient Navigation (CA/RPN)

Video (VID) BEHAVIORAL

An educational video about LCS

Stage 1: Repeated Text Messages and Video (TM+/VID); Stage 1: Repeated Text Messages, Chatbot, and Video (TM+/CA/VID)

Reactive Patient Navigation (RPN) BEHAVIORAL

RPN to help complete the LCS appointment. RPN requires the participant to initiate the PN request

Stage 2: Chatbot and Reactive Patient Navigation (CA/RPN)

Proactive Patient Navigation (PPN) BEHAVIORAL

Proactive patient navigation to help complete the LCS appointment. PPN does not require the participant to initiate the PN request and instead is a proactive call to the participant.

Stage 2: Chatbot and Proactive Patient Navigation (CA/PPN)

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Is currently a patient at participating CHCs
• Speak English or Spanish
• Current or former tobacco smoker
• Male or Female
• Age 50-80
• Electronic health records indicate they have not opted out of receiving text contact from the clinic
• Has a phone that can receive text messages

You may not qualify if:

• Persons with lung cancer or who have previously participated in a Shared Decision Making discussion with a health provider regarding lung cancer or have completed LCS.

Sponsors & Collaborators

• University of Utah: lead
• National Cancer Institute (NCI): collaborator
• Huntsman Cancer Institute: collaborator

Study Sites (1)

Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States

Location

MeSH Terms

Conditions

Lung Neoplasms

Interventions

Videotape Recording

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Tape Recording; Audiovisual Aids; Educational Technology; Technology; Technology, Industry, and Agriculture; Television

Study Officials

• David Wetter, PhD, MS

  Huntsman Cancer Institute/ University of Utah

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Indy Li, MS

CONTACT

801-213-5697; Indy.li@hci.utah.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 13, 2026
• First Posted: May 20, 2026
• Study Start (Estimated): August 1, 2026
• Primary Completion (Estimated): April 1, 2030
• Study Completion (Estimated): April 1, 2030
• Last Updated: May 20, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)