The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort

NCT07719751 | Enrolling By Invitation

• 1 other identifier: Mersin University 1
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins. The first six hours after birth are defined as the "adaptation period" for the newborn and consist of three stages. In this process, the first reactive period is particularly critical because the initial assessments determine the newborn's well-being. All organs, especially the respiratory and cardiovascular systems, are rapidly activated, and adaptation parameters are monitored. Evidence-based care interventions applied by midwives during this period directly affect the newborn's physiological stability and long-term health. The timing of umbilical cord clamping is a decisive factor in this adaptation. The World Health Organization recommends waiting at least 1 minute after birth for term and stable preterm infants, ideally with a delay of 1-3 minutes for clamping. Blood flow from the placenta to the baby continues for the first few minutes after birth. Therefore, not clamping the umbilical cord until 2-3 minutes have passed or until the cord pulse has completely stopped provides a physiological blood transfer. In this process, defined as "placental transfusion," a large portion of the blood passes to the baby within the first 3 minutes, contributing to an increase in circulatory volume and hemoglobin levels. In premature infants, stem cell transfer reduces complications and provides long-term benefits. In addition, this practice increases venous return, supporting heart filling and facilitating cardiorespiratory transition. In infants who undergo delayed clamping, oxygen saturation rises faster and irregular heartbeats are less common.

Conditions

Newborn Infant; Newborn Health; Delayed Cord Clamping

Keywords

Newborn; Prone; Left side lying; Position; Comfort

Outcome Measures

Primary Outcomes (1)

• Heart rate (pulse)

  Heart rate will be measured using a pulse oximeter during delayed umbilical cord clamping while the newborn is positioned either in the prone or left lateral position.

  During delayed umbilical cord clamping (within the first minutes after birth)

Secondary Outcomes (1)

• Oxygen saturation (SpO₂)

  During delayed umbilical cord clamping (within the first minutes after birth)

Other Outcomes (3)

• Respiratory pattern

  During delayed umbilical cord clamping (within the first minutes after birth)

• Skin color

  During delayed umbilical cord clamping (within the first minutes after birth)

• Newborn Comfort Behavior Scale score

  During delayed umbilical cord clamping (within the first minutes after birth)

Study Arms (2)

Prone position group

EXPERIMENTAL

Newborns should be placed in a prone position immediately after birth.

Other: Prone position

Left Side Lying Position Group

EXPERIMENTAL

Newborns should be placed on their left side immediately after birth.

Other: Left side lying position

Interventions

Prone position OTHER

After birth, the newborn will be positioned vertically on the linea line above the mother's mons pubis and monitored while lying prone.

Prone position group

Left side lying position OTHER

After birth, the newborn will be positioned vertically on the linea line above the mother's mons pubis and monitored while lying left side.

Left Side Lying Position Group

Eligibility Criteria

• Age: 0 Minutes+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• The newborn must have been born at term (≥37 weeks)
• Born from a singleton pregnancy
• Born vaginally
• The newborn must have been born alive
• The newborn must have spontaneous breathing
• The 1-minute Apgar score must be ≥7
• The mother must be able to communicate with the research
• The mother must have volunteered to participate in the study and given informed consent

You may not qualify if:

• Meconium-stained or foul-smelling amniotic fluid
• Episiotomy (3rd and 4th degree) and medical intervention during labor (vacuum, dystocia interventions, etc.)
• Suspicion of congenital anomalies or genetic diseases in the newborn
• History of known chronic diseases in the mother or baby (diabetes, hypertension, epilepsy, thyroid disease, etc.)

Sponsors & Collaborators

• Mersin University: lead

Study Sites (1)

Mersin University

Mersin, Turkey (Türkiye)

Location

Related Links

• Related Info
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MeSH Terms

Interventions

Prone Position

Intervention Hierarchy (Ancestors)

Posture; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor Doctor

Study Record Dates

• First Submitted: May 8, 2026
• First Posted: July 22, 2026
• Study Start: April 11, 2026
• Primary Completion (Estimated): September 20, 2026
• Study Completion (Estimated): November 2, 2026
• Last Updated: July 22, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)