Multıdımensıonal Effects Of Delayed Cord Clampıng and Mılkıng on Placental Processes

NCT06865391 | Completed DMC

• 1 other identifier: KahramanmaraşSIUI5
• Study Type: interventional
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

This study was conducted to evaluate the effects of delayed cord clamping and milking the umbilical cord of term babies after 90 seconds during vaginal birth on the newborn and the mother and to determine whether it is a suitable alternative method for cord management after birth. Methods: The study was conducted in the form of a randomized controlled design. The study was conducted in a hospital in eastern Turkiye between February -January 2025. The study was completed with 108 women who had vaginal delivery at term (DCC group n=36, UCM group n=36, control group n=36). Participants were assigned to groups by simple randomization. Data collection tools were used to collect demographic information, maternal hemoglobin, and hematocrit values, placental abruption time, newborn APGAR scores, umbilical cord pH levels, and day 7 hematological/biochemical parameters.

Conditions

18 Years and Over; Newborn Health; 37 or More Completed Weeks of Gestation

Keywords

delayed cord clamping; cord milking; placenta; clinical outcome; midwifery

Outcome Measures

Primary Outcomes (1)

• APGAR

  APGAR scores,Developed in 1953 by Dr Virginia Apgar for the quantitative assessment of the vitality of the newborn, the scoring system is used in almost all neonatal units as an easy and rapid method to determine the condition of the child at birth. Its aim is to encourage closer observation and to provide a more precise assessment of the clinical status of infants. According to the Apgar scoring system, the newborn is assessed at 1 and 5 minutes after birth and if necessary, the scoring is repeated every 5 minutes. Apgar scoring is based on 5 objective parameters: 1. peak heart rate, 2. respiratory pattern, 3. muscle tone, 4. skin colour, 5. response to stimulation. Each parameter is given 0, 1 and 2 points. The scores given for each parameter are summed. Values between 710 points are considered healthy newborns, while 4-6 points are considered moderate depression and 0-3 points are considered severe depression.

  5 minutes after birth

Study Arms (2)

Experimental

EXPERIMENTAL

Delayed cord clamping (DCC) was defined as clamping the umbilical cord 90 seconds after birth. A stopwatch was used to record the time of all interventions and was noted in the study protocol. Umbilical Cord Milking (UCM) is the process of grasping the umbilical cord towards the newborn before cutting the umbilical cord and pushing the blood towards the newborn 3-4 times within 20 seconds." In this group, early cord clamping (\<30 seconds) was performed after birth from 25-30 cm ahead of the newborn for a total of 4 times. UCM, with one hand, the cord was pinched and held closest to the placental end, the other hand was used to milk blood towards the infant where at the umbilical endpoint the cord was held. This served as one milking motion. The cord was then released at the placental end and allowed to refill over 1 to 2 seconds between each milking motion. This was repeated a total of 4 times. After milking, the cord was clamped and cut, and the neonate was handed over to

Behavioral: Delayed cord clamping

control group

NO INTERVENTION

standart care grup

Interventions

Delayed cord clamping BEHAVIORAL

Experimental

Eligibility Criteria

• Age: 18 Years - 49 Years
• Gender Eligibility Details: YES
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• being 18 years of age and older,
• having a single healthy newborn,
• having a 37-42 week pregnancy,
• having a baby in cephalic presentation, and
• having a first birth (nulliparous).

You may not qualify if:

• women with gestational anemia,
• having abnormal placentation (such as bleeding, hypertension),
• having a maternal hemorrhage,
• having Rh isoimmunization, and
• having a baby with a major congenital malformation

Sponsors & Collaborators

• Kahramanmaras Sutcu Imam University: lead

Study Sites (1)

Kahramanmaraş Sütçü İmama Universty

Kahramanmaraş Merkez, K.maraş, 461000, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Umbilical Cord Clamping

Intervention Hierarchy (Ancestors)

Delivery, Obstetric; Obstetric Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 14, 2025
• First Posted: March 7, 2025
• Study Start: March 20, 2025
• Primary Completion: March 28, 2025
• Study Completion: April 30, 2025
• Last Updated: August 14, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)