Combined Effects of Aerobic Exercise and Strength Training Among Post CABG Patients

NCT07713017 | Recruiting

• 1 other identifier: REC/RCR & AHS/25/0301
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

Title of study Combined effects aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients Objective (s) of the study To investigate the combined effects of aerobic exercise and strength training on functional capacity, cardiorespiratory fitness and quality of life with cardiac rehabilitation phase II among post CABG patients. Methodology (Design, sample size, sampling technique, Study setting, inclusion and exclusion criteria and Tool) Design: Randomized Controlled Trial Sample Size: 42 patients Sampling Technique: Convenient sampling technique will be used for selection of patient after that simple random sampling technique will be used for randomization among groups Study Setting: Hospital Setting SF-12, 6-min walk test, VO2 max, step test This study will not harm any fundamental rights of the patients and will consider and respect the preferences of patients.

Conditions

Coronary Atherosclerosis of Bypass Graft

Keywords

Aerobic Exercise; Strength Training; Functional Capacity; Cardiorespiratory Fitness; quality of life; cardiac rehab phase II

Outcome Measures

Primary Outcomes (3)

• Six-Minute Walk Test (6MWT)

  The six-minute walk test (6MWT) is a simple test that objectively evaluates a patient's functional capacity. This simple walk test is particularly applicable in the CAD population due to the risk of acute cardiac events associated with the gold standard maximal exercise testing for assessing functional capacity. The 6MWT requires a 30-m, flat, hard walking path, a stopwatch, a lap counter and two cones to mark the turning points. The patients were instructed to walk as far as possible along the pathway, in 6 minutes. During the test encouragement was not given and only asked about their conditions. At the end, total walked distance was measured and recorded

  5 weeks

• Step test

  The 6 min step test is a safe, valid, sensitive, and reproducible tool for evaluating cardiorespiratory fitness. The 6MST was shown to be a safe and reliable field test to assess exercise tolerance in a sample of very deconditioned adults at risk of CVD

  5 weeks

• Vo2 max

  Vo2 max was estimated using a graded exercise test. Oxygen consumption was measured using metabolic gas analyzer. In this research VO2 Max will be measured through a submaximal 6 mint walk test

  5 weeks

Secondary Outcomes (1)

• SF-12 Questionnaire

  5 weeks

Study Arms (2)

aerobic exercise

ACTIVE COMPARATOR

Aerobic exercise refers to the type of repetitive, structured physical activity that requires the body's metabolic system to use oxygen to produce energy. Aerobic exercise improves the capacity of the cardiovascular system to uptake and transport oxygen. Aerobic exercise training intensity is the most important variable in improving CRF during CR for most patients. Upper limb cycle ergometry is a form of aerobic exercise that can be tailored to individual needs. In the described protocol, patients perform 5 minutes of active exercise followed by 2 minutes of recovery, maintaining 20-30 rotations per minute. Moderate-intensity continuous aerobic training (MCT) is defined as 60% to 85% of peak heart rate and/or RPE of 12 to 14 on the 6 to 20 scale.

Behavioral: aerobic exercise

Aerobic Exercise and strength training

ACTIVE COMPARATOR

supervised exercise sessions 3 times per week for 6 months. Thus, in addition to the aerobic exercise training (as above), upper extremity resistance exercise was initially prescribed at 30% of 1RM, increasing to a maximum of 70% of 1RM by 4 weeks. Seventy percent of 1RM is in the comfortably hard range (5-7 on the Borg 1-10 scale, which is comparable to 13-15 on the 6-20 Borg scale). Each exercise repetition involved a slow controlled movement with approximately 2 sec of concentric lifting and 4 sec of eccentric lowering. Proper breathing techniques were enforced (with expiration during concentric lifting and inspiration during eccentric lowering).

Behavioral: Aerobic Exercise and strength training

Interventions

Aerobic Exercise and strength training BEHAVIORAL

1. Warm-up (5-10 minutes): - Light cardio (e.g., walking, jogging in place) - Dynamic stretching (e.g., arm circles, leg swings) 2. Aerobic Exercise (10-20 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week 3. Resistance Training (10-15 minutes): - Upper extremity exercises using resistance bands or light dumbbells - 2-3 sets of 8-12 repetitions per exercise - Intensity: 30-70% of 1RM - Frequency: 2-3 times per week Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)

Aerobic Exercise and strength training

aerobic exercise BEHAVIORAL

Aerobic Exercise Plan: 1. Warm-up (5 minutes): - Light arm movements (e.g., arm circles, shoulder rolls) - Dynamic stretching (e.g., arm swings) 2. Aerobic Exercise (20-30 minutes): - Arm cycle ergometer - Intensity: Moderate (40-60% of maximum heart rate reserve) - Frequency: 2-3 times per week 3. Cool-down (5-10 minutes): - Static stretching (e.g., bicep, triceps, chest muscles)

aerobic exercise

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both genders (male, female)
• Patient who underwent a successful CABG (no complications during surgery and/or in the following weeks)
• Patients willing to participate in the phase II cardiac rehabilitation program.
• Age between 30 to 60 years
• Patients having no impairment in the musculoskeletal system

You may not qualify if:

• Patients with unstable congestive heart failure and symptoms of significant myocardial ischemia, including chest pain
• Patients with uncontrolled diabetes mellitus or hypertension.
• Patients with any motor or neurological impairment
• Patients with severe disturbance of consciousness, having an orthopedic problem and critical limb ischemia

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Imran Idrees teaching hospital sialkot

Sialkot, Punjab Province, 40100, Pakistan

RECRUITING

MeSH Terms

Interventions

Exercise; Resistance Training

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human

Study Officials

• Arjumand Bano, MS

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Iqbal Tariq, pHD

CONTACT

333826752; iqbal.tariq@riphah.edu.pk

Misdaq Batool, MS PT

CONTACT

03496166611; misdaaqbatool@yahoo.com.ph

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2026
• First Posted: July 20, 2026
• Study Start: June 1, 2026
• Primary Completion: August 1, 2026
• Study Completion: August 1, 2026
• Last Updated: July 20, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)