Effects of Aerobic Training With and Without Sniff Maneuver

NCT07064057 | Completed

• 1 other identifier: REC/RCR&AHS/23/0341
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This study was planned to assess effects of Aerobic training with and without Sniff maneuver on Dyspnea, Functional capacity and Quality of life among Asthma Patients. Results showed that when aerobic training done along with the sniff maneuver had proven to be the more effective choice of treatment in reducing severity level of asthma along with the decreased perceived dyspnea and improved quality of life and functional capacity.

Conditions

Asthma

Keywords

Exercise; Dyspnea; Sniff maneuver; Functional capacity; Quality of life

Outcome Measures

Primary Outcomes (3)

• Euro QOL 5 Dimensional Questionnaire

  The EQ-5D is the most often used multi attribute utility (MAU) instrument in cost effectiveness evaluations for evaluating health-related quality of life. The descriptive system is made up of five features: mobility, self-care, regular activities, pain/discomfort, and anxiety/depression. The terms "not /no problems," "slight problems," "moderate problems," "severe problems," and "unable to" (mobility, self-care, regular activities) are used to describe the five levels in each category. Other terms used are "extreme" (pain/depression) or "extremely" (anxiety/depression). The patient is questioned to rate his or her current state of health by checking the box next to the statement that most closely matches each of the five dimensions.

  6 weeks

• Borg Scale

  Dyspnea was checked by Borg Scale.

  6 weeks

• 6 Min Walk Test

  Functional capacity was checked by 6 min walk test Stopwatch to calculate overall activity time

  6 weeks

Study Arms (2)

Aerobic exercises along with sniff maneuver

EXPERIMENTAL

Aerobic exercises on a stationary bike or electric treadmill three times a week for six weeks.

Other: Aerobic exercise combined with the sniff maneuver technique

Aerobic exercises only

ACTIVE COMPARATOR

The treadmill was used for both the warm-up and cooling-down phases.

Other: Aerobic exercise

Interventions

Aerobic exercise combined with the sniff maneuver technique OTHER

Aerobic exercises on a stationary bike or electric treadmill three times a week for six week. Five minutes of stretching, concentrated on the main lower limb muscle groups, were followed by a ten-minute warm-up, twenty minutes of training during the first two weeks and thirty minutes during the third to sixth week, and finally, a five-minute cooling-down phase..

Aerobic exercises along with sniff maneuver

Aerobic exercise OTHER

The treadmill was used for both the warm-up and cooling-down phases. Heart rate was kept between 40% and 50% of maximum heart rate for these sessions. (5) To achieve a moderate exertion (rated as 11--13 on the Borg scale) and/or a moderate dyspnea (rated as 3---4 on the modified Borg scale), the intensity of the aerobic training was progressively increased.

Aerobic exercises only

Eligibility Criteria

• Age: 35 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 35 to 50
• Moderate to severe asthma (FE ratio: 50 to 65%, ˂50%)

You may not qualify if:

• Patient with Cardiovascular(5)
• Musculosketal disorders (5)
• Smokers were excluded
• Patient with foot drop
• Osteoarthritis
• Low back pain
• Post traumatic history
• Patients who was suffer physical or mental illness were be excluded
• If participant engage another exercise program were be excluded Mild asthma patient

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Al-Zahra Medical Complex

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (4)

• Moraes-Ferreira R, Brandao-Rangel MAR, Gibson-Alves TG, Silva-Reis A, Souza-Palmeira VH, Aquino-Santos HC, Frison CR, Oliveira LVF, Albertini R, Vieira RP. Physical Training Reduces Chronic Airway Inflammation and Mediators of Remodeling in Asthma. Oxid Med Cell Longev. 2022 Oct 20;2022:5037553. doi: 10.1155/2022/5037553. eCollection 2022.

  PMID: 36312895 BACKGROUND

• Hansen ESH, Pitzner-Fabricius A, Toennesen LL, Rasmusen HK, Hostrup M, Hellsten Y, Backer V, Henriksen M. Effect of aerobic exercise training on asthma in adults: a systematic review and meta-analysis. Eur Respir J. 2020 Jul 30;56(1):2000146. doi: 10.1183/13993003.00146-2020. Print 2020 Jul.

  PMID: 32350100 BACKGROUND

• Andrade LB, Britto MC, Lucena-Silva N, Gomes RG, Figueroa JN. The efficacy of aerobic training in improving the inflammatory component of asthmatic children. Randomized trial. Respir Med. 2014 Oct;108(10):1438-45. doi: 10.1016/j.rmed.2014.07.009. Epub 2014 Aug 29.

  PMID: 25231109 BACKGROUND

• Abdelbasset WK, Alsubaie SF, Tantawy SA, Abo Elyazed TI, Kamel DM. Evaluating pulmonary function, aerobic capacity, and pediatric quality of life following a 10-week aerobic exercise training in school-aged asthmatics: a randomized controlled trial. Patient Prefer Adherence. 2018 Jun 15;12:1015-1023. doi: 10.2147/PPA.S159622. eCollection 2018.

  PMID: 29942118 BACKGROUND

MeSH Terms

Conditions

Asthma; Motor Activity; Dyspnea

Interventions

Exercise

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Behavior; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Hira Shaukat, Mphill

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: July 14, 2025
• Study Start: August 3, 2023
• Primary Completion: October 1, 2023
• Study Completion: December 1, 2023
• Last Updated: July 14, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)