Aerobic Training With and Without Resistance Training in Polycystic Ovarian Syndrome

NCT06198348 | Completed

• 1 other identifier: S22C14G92023
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

Polycystic ovary syndrome (PCOS) characterized by a chronic disorder in ovulation along with hyperandrogenism has become one of the most common endocrine disorders in women of reproductive age with an estimated 5%-15% prevalence. It has the symptoms such as menstrual disorders, infertility, hyperandrogenism, obesity, hirsutism and acne. PCOS is linked to Psychological morbidities e.g. increased risk of stress, depression, low self-esteem, poor body image, and reduced health-related quality of life. Approximately 75% of people with PCOS have a fat accumulation in the central area of the body.

Conditions

Polycystic Ovary Syndrome

Keywords

Polycystic ovarian syndrome; Quality of life; Waist to Hip Ratio; Aerobic Exercise; Resistance Training

Outcome Measures

Primary Outcomes (3)

• SF-36 Questionnaire

  QoL was assessed by the validated Portuguese version of the self-reported MOS SF-36, which consists of eight subscales: (1) Physical Role Function, (2) Physical Functioning, (3) Bodily Pain, (4) General Health Perception, (5) Vitality, (6) Social Role Functioning, (7) Emotional Role functioning, and (8) Mental Health. A substantial body of research supports the reliability of the SF-36 measurements.validity of SF-36 Questionnaire is 0.90 Subscale scores range from 0 to 100, with a lower score indicating lower QoL for that subscale.

  8 weeks

• Self-administered PCOSQ

  All the participants filled up the self-administered PCOSQ. PCOS Questionnaire has 26 items divided into 5 domains: emotions (8 items), body hair (5 items), weight (5 items), infertility (4 items), and menstrual problems (4 items). Each question is associated with a 7point scale in which 7 represents optimal function and 1 represents the poorest Function. PCOSQ dimensions were internally reliable with Cronbach's a scores ranging from 0.70 to 0.97.

  8 weeks

• Measuring Tape

  Waist circumference (WC) was measured with the participant in the standing position, with arms at the side of the body, feet together, and with a relaxed abdomen. For WC, a horizontal measurement was obtained on the narrower part of the dorsum (above the navel and below the xiphoid process. Hip circumference (HC) was measured using the same positioning, as the region with the largest circumference of the buttocks. Waist-to-hip ratio (WHR) was measured by dividing the WC value by the HC value

  8 weeks

Study Arms (2)

Aerobic Exercise (Control Group)

OTHER

Group A will receive Aerobic exercise plan. The treatment will be given with the frequency of 3 times per week for 8 weeks. Treatment sessions will be of 30 minutes with short resting intervals

Other: Aerobic Exercise

Aerobic exercise with resistance training (Experimental Group)

EXPERIMENTAL

Group B will receive aerobic and resistance exercise plan. The frequency of treatment will be as same as that of aerobic exercise program i.e. 3 times a week for 8 weeks. Treatment sessions will be of 45 minutes with short resting intervals

Other: Aerobic Exercises with Resistance training

Interventions

Aerobic Exercise OTHER

Treatment Protocol to Group A It consists of patients who will receive aerobic exercise sessions 3 times per week for 8 weeks. Every session will be of 30 minutes. It will include warm up phase, active phase and cool down phase Warm-up phase: In which each participant will walk at 80 m/min at for 5 min. Active phase: Brisk walking or treadmill: In which each participant will perform brisk walking for 15 mints initially. After that gradually duration of brisk walking will increase.

Aerobic Exercise (Control Group)

Aerobic Exercises with Resistance training OTHER

These groups will perform these exercises: Aerobic exercise +resistance exercises Exercise Session: 3 days per week Time of exercise session: 30-45 min After following protocol of aerobic exercise as mentioned above the subjects will perform resistance exercises. These Exercises will perform: 1. Leg press (dual leg press): Leg press targets the Glutes "Quadriceps or quads .but they also work your "Hamstrings". 2. Crunches: Crunches Target the abdominal muscles specifically rectus abdominis and obliques. 3. Squats: Squats targets the adductor muscles of the hip, glutes and rectus abdominis muscle Leg Extension Total Exercise plan for 12 weeks: 1-2 weeks: Repitations: 10-15 times No of sets: 1 set Resistance: minimum 3-4 weeks: Repitations: 10-15 times No of sets: 2 set Resistance: moderate 5-6 weeks: Repitations: 15-16 times No of sets: 2 set Resistance: moderate 7-8 weeks: Repitations: 15-16 times No of sets: 2 set

Aerobic exercise with resistance training (Experimental Group)

Eligibility Criteria

• Age: 18 Years - 40 Years
• Gender Eligibility Details: Polycystic Ovary Syndrome only occurs in females.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-40yrs
• Waist to hip ratio \>87(20)
• Women who are diagnosed according to Rotterdam criteria e.g. oligo/anovulation, hyperandrogenism, and polycystic ovaries.(21)
• Female who physically able to performs exercise

You may not qualify if:

• Women who are smoking and using drugs for depression.
• Married women
• Women with other pathological conditions like diabetes and thyroid diseases.
• Females who are not able to perform resistant exercise

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Jinnah Hospital

Lahore, Punjab Province, 44000, Pakistan

Location

MeSH Terms

Conditions

Polycystic Ovary Syndrome

Interventions

Exercise; Resistance Training

Condition Hierarchy (Ancestors)

Ovarian Cysts; Cysts; Neoplasms; Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Gonadal Disorders; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human

Study Officials

• Faiza Taufiq, PPDPT

  Riphah International University, Senior Lecturer

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 26, 2023
• First Posted: January 10, 2024
• Study Start: March 15, 2023
• Primary Completion: March 15, 2024
• Study Completion: March 15, 2024
• Last Updated: April 19, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)