NCT07693504

Brief Summary

This single-center, single-blind, three-arm randomized controlled trial aims to compare the effects of weekend-concentrated exercise, regularly distributed exercise, and usual lifestyle on aerobic capacity and skeletal muscle strength in sedentary female university students. Sixty participants aged 18 to 25 years will be randomly assigned in a 1:1:1 ratio to a weekend warrior group, a regular exercise group, or a control group. The intervention will last 8 weeks. Both exercise groups will complete 150 minutes of moderate-intensity exercise per week, combining resistance exercise and jogging, but the exercise sessions will be distributed differently across the week. The control group will maintain its usual lifestyle without receiving the prescribed exercise intervention. The primary outcomes are peak oxygen uptake and isokinetic peak torque. Secondary outcomes include body composition, maximal heart rate, maximal power and time to exhaustion, 12-minute run performance, isokinetic mean torque, physical activity, sleep quality, exercise self-efficacy, emotional status, cognitive function, adherence, feasibility, and exercise-related adverse events.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
14mo left

Started Jul 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress7%
Jul 2026Oct 2027

Study Start

First participant enrolled

July 1, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

July 3, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 9, 2026

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

July 13, 2026

Status Verified

July 1, 2026

Enrollment Period

1.3 years

First QC Date

July 3, 2026

Last Update Submit

July 10, 2026

Conditions

Keywords

Weekend Warrior ExerciseAerobic CapacitySkeletal Muscle StrengthFemale University StudentsExercise DistributionModerate-Intensity Exercise

Outcome Measures

Primary Outcomes (2)

  • Change in Peak Oxygen Uptake (VO2peak)

    Peak oxygen uptake will be assessed during a graded cardiopulmonary exercise test. VO2peak will be recorded in milliliters of oxygen per kilogram of body mass per minute (mL/kg/min). The change from baseline to the end of the 8-week intervention will be compared among the three study groups.

    Baseline (week 0) and post-intervention (week 8)

  • Change in Isokinetic Peak Torque

    Skeletal muscle peak torque will be assessed using an isokinetic dynamometer and recorded in Newton-meters (N·m). The change from baseline to the end of the 8-week intervention will be compared among the three study groups.

    Baseline (week 0) and post-intervention (week 8)

Secondary Outcomes (11)

  • Change in Body Weight

    Baseline (week 0) and post-intervention (week 8)

  • Change in Body Mass Index

    Baseline (week 0) and post-intervention (week 8)

  • Change in Body Fat Percentage

    Baseline (week 0) and post-intervention (week 8)

  • Change in Waist-to-Hip Ratio

    Baseline (week 0) and post-intervention (week 8)

  • Change in Maximal Heart Rate

    Baseline (week 0) and post-intervention (week 8)

  • +6 more secondary outcomes

Study Arms (3)

Weekend Warrior Exercise Group

EXPERIMENTAL

Participants will complete an 8-week weekend-concentrated exercise program. They will exercise on two consecutive days per week, completing 30 minutes of resistance exercise and 45 minutes of jogging on each exercise day, for a total of 75 minutes per day and 150 minutes per week.

Behavioral: Weekend Warrior Exercise

Regular Exercise Group

ACTIVE COMPARATOR

Participants will complete an 8-week regularly distributed exercise program. They will exercise on three days per week, completing 20 minutes of resistance exercise and 30 minutes of jogging during each session, for a total of 50 minutes per session and 150 minutes per week.

Behavioral: Regularly Distributed Exercise

Control Group

NO INTERVENTION

Participants will maintain their usual study and lifestyle habits during the 8-week study period and will not receive the exercise intervention prescribed by the study. Their participation in additional structured exercise will be monitored.

Interventions

Participants will complete an 8-week weekend-concentrated exercise program on two consecutive days per week. On each exercise day, participants will perform 30 minutes of resistance exercise and 45 minutes of moderate-intensity jogging, resulting in 75 minutes per day and 150 minutes per week. Resistance exercises will target the lower limbs, core, and major muscle groups and may include squats, lunges, glute bridges, calf raises, and planks. Jogging intensity will be maintained at approximately 60% to 75% of maximal heart rate or a rating of perceived exertion of 12 to 14. Each session will include warm-up and cool-down activities.

Weekend Warrior Exercise Group

Participants will complete 150 minutes of moderate-intensity exercise per week for 8 weeks, distributed across three days. Each session will include 20 minutes of resistance exercise targeting the lower limbs, core, and major muscle groups, followed by 30 minutes of jogging. The exercise content, intensity-control principles, and safety requirements will be comparable to those of the weekend warrior group.

Regular Exercise Group

Eligibility Criteria

Age18 Years - 25 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female university students aged 18 to 25 years.
  • Self-reported sedentary time of at least 6 hours per day, further assessed using the International Physical Activity Questionnaire (IPAQ).
  • No cardiovascular, pulmonary, neurological, metabolic, or musculoskeletal diseases.
  • Relatively regular menstrual cycles.
  • Able to understand the study procedures, willing to complete the intervention and assessments, and willing to provide written informed consent.

You may not qualify if:

  • Any condition identified through clinical assessment or health screening that makes participation in moderate-intensity exercise or exercise-to-exhaustion testing inappropriate.
  • Participation in regular exercise training, a systematic weight-loss or body-shaping program, or another exercise intervention study within the previous 3 months.
  • Recent substantial body-weight fluctuations that may affect body-composition assessment.
  • Cardiovascular, pulmonary, neurological, metabolic, or musculoskeletal diseases, or current use of medications that may affect exercise performance, heart-rate responses, or muscle function.
  • Irregular menstrual cycles.
  • Inability to complete the 8-week intervention, post-intervention assessments, or required study records.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chongqing Normal University

Chongqing, Chongqing Municipality, 401331, China

Location

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Kaixiang Zhou

    Chongqing Normal University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Due to the nature of the exercise interventions, participants and exercise supervisors cannot be blinded. Outcome assessors and data analysts will be blinded to group allocation.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned in a 1:1:1 ratio to the weekend warrior exercise group, regular exercise group, or control group. The two exercise groups will complete the same total weekly exercise duration but will differ in how the exercise sessions are distributed across the week.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Graduate Student

Study Record Dates

First Submitted

July 3, 2026

First Posted

July 9, 2026

Study Start

July 1, 2026

Primary Completion (Estimated)

October 1, 2027

Study Completion (Estimated)

October 1, 2027

Last Updated

July 13, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared. Study findings will be reported only in aggregate or anonymized form in academic publications, conference presentations, and research reports, in accordance with the approved protocol and informed consent.

Locations