Investigation of the Effects of Mixed Reality Application on the Upper Extremity in Individuals With Hemiparetic Stroke

NCT07693413 | Completed DMC

• 1 other identifier: HasanKU-FTR-01
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effectiveness of mixed reality (MR)-based rehabilitation applications in improving motor functions, trunk stability, and upper extremity performance in stroke patients. The use of mixed reality technology in addition to traditional rehabilitation methods provides individuals with an interactive and motivating rehabilitation environment that mimics real-life activities. The study aims to increase functional independence, improve motor skills and trunk stability, enhance upper extremity functions, facilitate return to daily living activities, increase adaptation and motivation to the rehabilitation process, and provide a repeatable, safe, and patient-centered exercise environment in stroke patients. This thesis aims to contribute to both clinical physiotherapy practice and the literature by evaluating the applicability of mixed reality technology, a patient-centered and innovative rehabilitation approach, as a treatment option in neurological rehabilitation. The study's objective in improving upper extremity function is to make the individual less dependent on others while performing daily living activities, to instill a sense of self-sufficiency, and to enhance existing skills to make them more functional.

Conditions

Stroke

Keywords

stroke; rehabilitation; virtual reality; upper extremity

Outcome Measures

Primary Outcomes (1)

• Modified Box and Block Test - mBBT

  The individual performs this test with both their dominant and non-dominant hand. mBBT reflects a direct assessment of individuals' upper extremity functional performance based on the number of blocks transferred from one compartment to the other within 30 seconds. At the end of the time period, the number of blocks transferred to the opposite compartment is recorded.

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

Secondary Outcomes (6)

• L-Shape Test

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

• Action Research Arm Test -ARAT

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

• İmpairment Scale - TIS

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

• BlazePod

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

• Specific Quality of Life Scale (SS-QOL)

  Baseline (prior to the start of treatment) and immediately after completion of the 8 week invertion.

Study Arms (2)

Control group

ACTIVE COMPARATOR

Control group, receiving traditional treatment

Other: Traditional therapy

Intervention group

ACTIVE COMPARATOR

Intervention group, receiving virtual reality treatment

Other: virtual reality

Interventions

Traditional therapy OTHER

The treatment will last 8 weeks, 3 days a week, with each session lasting 30 minutes. Participants will receive traditional physiotherapy treatment, including upper extremity strengthening, motor skills exercises, and balance exercises.

Control group

virtual reality OTHER

The treatment will last 8 weeks, 3 days a week, with each session lasting 30 minutes. Participants will be playing Reach VR within the Meta Quest 3 using the eye.

Intervention group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals aged 18-65 who have experienced a stroke.
• At least 6 months must have passed since the stroke.
• FIM independence scale score of 50 or higher.
• Fugl-Meyer Upper Extremity Assessment (FMA) score between 23-66.
• Mini Mental Test score above 24.

You may not qualify if:

• Presence of current epileptic seizures.
• Upper extremity spasticity 3-4.
• Visual or hearing loss that would affect the study.
• Individuals who have experienced multiple strokes.

Sponsors & Collaborators

• Emine Ece Bedir Ayar: lead

Study Sites (1)

Hasan Kalyoncu Univercity

Gaziantep, Gaziantep, 27000, Turkey (Türkiye)

Location

Related Publications (2)

• Thijs L, Voets E, Denissen S, Mehrholz J, Elsner B, Lemmens R, Verheyden GS. Trunk training following stroke. Cochrane Database Syst Rev. 2023 Mar 2;3(3):CD013712. doi: 10.1002/14651858.CD013712.pub2.

  PMID: 36864008 RESULT

• Deathe AB, Miller WC. The L test of functional mobility: measurement properties of a modified version of the timed "up & go" test designed for people with lower-limb amputations. Phys Ther. 2005 Jul;85(7):626-35.

  PMID: 15982169 RESULT

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• KEZBAN YİĞİTER, PROFESSOR

  HASAN KALYONCU UNIVERCITY

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Physiotherapist

Model Details: One group was a control group receiving traditional treatment, and the other group was an intervention group receiving virtual reality treatment. A total of two groups.

Study Record Dates

• First Submitted: June 27, 2026
• First Posted: July 9, 2026
• Study Start: January 1, 2026
• Primary Completion: March 1, 2026
• Study Completion: May 30, 2026
• Last Updated: July 9, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)