Multicomponent Exercise and Frailty in Nursing Home Residents

NCT07686146 | Completed

• 1 other identifier: CEEAH-UAB-5654
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

Frailty is common among older adults living in nursing homes and increases the risk of falls, disability, and loss of independence. However, there is limited evidence on practical and feasible exercise programs adapted to this population. This study evaluated the effects of a multicomponent exercise program combining strength and balance training in residents aged 65 years and older. Participants were assigned to either an intervention group, which performed supervised exercise sessions twice a week for 8 weeks, or a control group, which continued their usual activities. The main outcome was frailty, measured using the Short Physical Performance Battery. Other outcomes included balance, functional independence, sarcopenia, fear of falling, and number of falls. This study was retrospectively registered.

Conditions

Balance Impairment; Sarcopenia in Elderly; Frailty at Older Adults; Fall Risk; Functional Decline

Keywords

multicomponent exercise; frailty; older adults; nursing homes; balance training; functional performance; fall prevention; physical therapy; institutionalizad elderly

Outcome Measures

Primary Outcomes (1)

• Frailty assessed by the Short Physical Performance Battery (SPPB)

  Frailty was measured using the Short Physical Performance Battery (SPPB), which includes assessments of balance, gait speed, and chair rise performance. Total scores range from 0 to 12, with higher scores indicating better physical performance.

  Baseline to 8 weeks

Secondary Outcomes (5)

• Balance assessed by the Performance-Oriented Mobility Assessment (POMA)

  Baseline, 8 weeks, and 20 weeks

• Sarcopenia assessed by SARC-F

  Baseline, 8 weeks, and 20 weeks

• Functional independence assessed by the Barthel Index

  Baseline, 8 weeks, and 20 weeks

• Fear of falling assessed by Short FES-I

  Baseline, 8 weeks, and 20 weeks

• Number of falls

  Throughout the 20-week study period

Study Arms (2)

Multicomponent Exercise Program (BASE)

EXPERIMENTAL

Participants engaged in a supervised multicomponent exercise program including strength and balance training, performed twice weekly for 8 weeks.

Behavioral: Multicomponent Exercise Program (BASE)

Usual Care

OTHER

Participants continued their usual care and routine activities provided by their nursing homes.

Other: Usual Care

Interventions

Multicomponent Exercise Program (BASE) BEHAVIORAL

A supervised multicomponent exercise program including strength and balance training, performed twice weekly for 8 weeks. Each session lasted 30-40 minutes and included warm-up, strength exercises, and progressively adapted balance tasks based on individual capacity.

Multicomponent Exercise Program (BASE)

Usual Care OTHER

Participants continued their usual care and routine physical activities provided by the nursing homes without additional structured intervention.

Also known as: Standard care

Usual Care

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Aged 65 years or older
• Living in a nursing home
• Ability to walk at least 10 meters (with or without assistive devices)
• Mini-Mental State Examination (MMSE) score ≥19

You may not qualify if:

• Neurodegenerative diseases
• Advanced dementia
• Parkinson's disease
• Hemodynamic instability
• Lower limb fractures under rehabilitation within the past year

Sponsors & Collaborators

• Escoles Universitaries Gimbernat: lead

Study Sites (1)

Escoles Universitàries Gimbernat

Sant Cugat del Vallès, Barcelona, 08174, Spain

Location

MeSH Terms

Conditions

Frailty

Interventions

Alkalies; Standard of Care

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Inorganic Chemicals; Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Masking Details: No blinding was used due to the nature of the intervention.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Model Details: Participants were allocated by residential center to either an intervention group or a control group in a non-randomized parallel design. The intervention group received a multicomponent exercise program, while the control group continued usual care.

Study Record Dates

• First Submitted: June 25, 2026
• First Posted: July 7, 2026
• Study Start: November 30, 2021
• Primary Completion: January 31, 2022
• Study Completion: December 31, 2022
• Last Updated: July 7, 2026

Record last verified: 2026-07

Locations

ES (1)