Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Health Services Research Intervention
Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System (Kentucky QUILS™ Implementation): HSR Intervention
1 other identifier
interventional
35,500
1 country
17
Brief Summary
This clinical trial studies statewide optimization of lung cancer screening (LCS) in Kentucky using the Quality Implementation of Lung Screening (QUILS™) System. Data from the Kentucky Cancer Registry shows that LCS implementation has contributed to a rapid decline in late-stage lung cancer diagnosis at twice the national average. Further, the declines are more than three times the national average decline in Kentucky's Central Appalachian region. Kentucky-based multilevel initiatives are needed to expand and accelerate this leading role and extend the LCS opportunity to more Kentuckians who are at increased risk of lung cancer. This trial may be able to accelerate optimal high-quality implementation of LCS utilizing the QUILS™ System and reduce the burden of lung cancer by assisting lung cancer screening programs located throughout Kentucky in implementing best practices in lung cancer screening by integrating the QUILS™ System domains and elements into their screening programs.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Apr 2025
Longer than P75 for not_applicable
17 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2025
CompletedFirst Submitted
Initial submission to the registry
June 26, 2026
CompletedFirst Posted
Study publicly available on registry
July 6, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2028
July 6, 2026
June 1, 2026
2.2 years
June 26, 2026
June 26, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Change in Quality Improvement Lung Cancer Screening (QUILS) Index Assessment Score
The QUILS Index Assessment is a program-level measure of lung cancer screening implementation quality. Scores range from 0 to 95, with a higher score indicating higher quality implementation of lung cancer screening practices. The outcome measure is the change in total QUILS Index score from Baseline to 12 months.
Baseline and Month 9
Study Arms (1)
QUILS System Implementation
EXPERIMENTALParticipants who are members of the lung cancer screening program (LCSP) team will receive the QUILS System intervention, including completion of the QUILS Index Assessment, participation in QUILS Audit and Feedback presentations, access tot the QUILS Resource Portal and site specific action plans, and formative evaluation interviews.
Interventions
The QUILS System is a health services research intervention designed to improve the quality of lung cancer screening programs. The intervention includes QUILS Index Assessment, QUILS Audit and Feedback Report and Presentation, QUILS Resource Portal, site-specific action plans, and formative evaluation activities.
Eligibility Criteria
You may qualify if:
- Member of a participating Lung Cancer Screening Program (LCSP) team or administrator
- Willing to participate in the QUILS Index Assessment Survey process
- Willing to participate in the QUILS Audit Feedback presentations
- Willing to participate in formative evaluation interviews
You may not qualify if:
- Unwilling to participate in the QUILS Index Assessment Survey process
- Unwilling to participate in the QUILS Audit Feedback presentations
- Unwilling to participate in formative evaluation interviews
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Timothy Mullettlead
Study Sites (17)
King's Daughter's Medical Center
Ashland, Kentucky, 41101, United States
Taylor Regional Hospital
Campbellsville, Kentucky, 42718, United States
St. Elizabeth Healthcare
Edgewood, Kentucky, 41017, United States
Georgetown Cancer Treatment Cancer
Georgetown, Kentucky, 40324, United States
TJ Samson Community Hospital
Glasgow, Kentucky, 42141, United States
Hazard Appalachian Regional Healthcare Medical Center
Hazard, Kentucky, 41701, United States
Lexington VA Health Care System
Lexington, Kentucky, 40502, United States
St. Joseph Health (Catholic Health Initiatives)
Lexington, Kentucky, 40504, United States
University of Kentucky Markey Cancer Center
Lexington, Kentucky, 40506, United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202, United States
Meadowview Regional Medical Center
Maysville, Kentucky, 41056, United States
Saint Claire Regional Medical Center
Morehead, Kentucky, 40351, United States
Rockcastle Regional Hospital
Mount Vernon, Kentucky, 40456, United States
Owensboro Health Mitchell Memorial Cancer Center
Owensboro, Kentucky, 42303, United States
Mercy Health - Paducah Cancer Center
Paducah, Kentucky, 42003, United States
Lake Cumberland Regional Hospital
Somerset, Kentucky, 42501, United States
Clark Regional Medical Center
Winchester, Kentucky, 40391, United States
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
June 26, 2026
First Posted
July 6, 2026
Study Start
April 1, 2025
Primary Completion (Estimated)
June 1, 2027
Study Completion (Estimated)
June 1, 2028
Last Updated
July 6, 2026
Record last verified: 2026-06