The Impact of Good Versus Poor Sleep Quality on Quality of Life, Depression, and Fatigue in Individuals With Multiple Sclerosis

NCT07681037 | Completed

• 1 other identifier: 2025/278
• Study Type: observational
• Target: 121
• Locations: 1 country
• Sites: 1

Brief Summary

This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis. The study was conducted at the Multiple Sclerosis (n=121) Outpatient Clinic of the Health Research and Application Center at the Trakya University between July 15, 2025, and December 30, 2025, with patients who were receiving outpatient treatment, had no communication difficulties, and agreed to participate in the study. These patients were provided with an "Informed Consent Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.

Conditions

Quality of Life; Depression; Multiple Sclerosis

Keywords

Fatigue; Depression; Quality of life; Multiple Sclerosis; Sleep Quality

Outcome Measures

Primary Outcomes (1)

• determining sleep quality

  To evaluate the association between sleep quality and quality of life, depression, and fatigue in individuals with multiple sclerosis.

  6 month

Study Arms (1)

Multiple Sclerosis

Data were collected using a patient Information Form, the Pittsburgh Sleep Quality Index (PSQI), the

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Having a confirmed diagnosis of multiple sclerosis

You may qualify if:

• Being over 18 years of age
• Having a confirmed diagnosis of multiple sclerosis
• Being a registered patient at a multiple sclerosis clinic
• Not experiencing communication difficulties
• Volunteering to participate in the study

You may not qualify if:

• Being under 18 years of age
• Not having a confirmed diagnosis of multiple sclerosis
• Not currently attending a multiple sclerosis clinic
• Experiencing communication difficulties
• Not volunteering to participate in the study

Sponsors & Collaborators

• Trakya University: lead

Study Sites (1)

Trakya University Faculty of Medicine Dean'S Office Building

Merkez, Edirne, 22100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Depression; Multiple Sclerosis; Fatigue; Sleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Mental Disorders

Study Officials

• Ayfer Gunes

  Trakya University Medical Research and Application Centre, Department of Neurology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr. (PhD), RN, Principal Investigator

Study Record Dates

• First Submitted: June 10, 2026
• First Posted: July 2, 2026
• Study Start: July 15, 2025
• Primary Completion: December 30, 2025
• Study Completion: January 5, 2026
• Last Updated: July 2, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF

Locations

TU (1)