Manual Lymphatic Drainage on Pressure Injuries

NCT07677761 | Not Yet Recruiting

• 1 other identifier: Pressure Injury - MLD
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Pressure injuries are a significant health problem, often resulting from pressure, friction, and impaired tissue perfusion, and are particularly common in individuals in intensive care, those with immobility, and those with chronic diseases. The literature extensively addresses interventions such as pressure reduction, the use of appropriate support surfaces, wound care practices, and nutritional support in the prevention and treatment of pressure injuries. However, the role of manual therapies aimed at improving circulation and lymphatic flow, such as manual lymphatic drainage (MLD), in pressure injuries has been examined in a limited number of studies. This research aims to fill a significant gap in the literature by evaluating the potential effects of manual lymphatic drainage on reducing edema, improving tissue perfusion, and supporting the wound healing process in individuals with pressure injuries.

Conditions

Pressure Injuries; MANUEL LENFATIK DRENAJ

Outcome Measures

Primary Outcomes (1)

• Effect of manual lymphatic drainage

  The primary aim of this study is to evaluate the effect of manual lymphatic drainage on the healing level of pressure injuries. Wound healing will be assessed considering the wound stage (Stage 1-2-3-4, unstageable stage, and deep tissue injury) and size (length\*width\*depth).

  3 months

Study Arms (2)

Manual lymphatic drainage group

ACTIVE COMPARATOR

Individuals will be randomly assigned to intervention and control groups in a 1:1 ratio via the website random.org. The Bates-Jensen Wound Assessment Tool will be administered to all individuals by the researchers. The size of the wound (length\*depth\*width) will be measured and recorded. Standard care will be applied to the control group. The experimental group will receive standard care along with manual lymphatic drainage according to the protocol below. Afterwards, the Bates-Jensen Wound Assessment Tool will be administered to all individuals by the researchers, and the size of the wound (length\*depth\*width) will be measured and recorded.

Other: Experimental

comparison group

ACTIVE COMPARATOR

Other: Control

Interventions

Experimental OTHER

Individuals will be randomly assigned to intervention and control groups in a 1:1 ratio via the website random.org. The Bates-Jensen Wound Assessment Tool will be administered to all individuals by the researchers. The size of the wound (length\*depth\*width) will be measured and recorded. Standard care will be applied to the control group. The experimental group will receive standard care along with manual lymphatic drainage according to the protocol below. Afterwards, the Bates-Jensen Wound Assessment Tool will be administered to all individuals by the researchers, and the size of the wound (length\*depth\*width) will be measured and recorded.

Manual lymphatic drainage group

Control OTHER

Standard care practices will include regular position changes for patients, use of supportive surfaces to reduce pressure, maintenance of skin integrity, and keeping the wound area clean. Wound cleaning will be performed with sterile solutions, appropriate debridement methods will be applied in the presence of necrotic tissue, and suitable dressing materials will be selected according to the condition of the wound bed. In addition, patients' nutritional status, hydration level, and signs of infection will be regularly assessed, and necessary supportive treatments will be provided.

comparison group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Presence of pressure injury in the sacrum region
• Volunteer to participate in the study
• Being over 18 years of age
• Being hospitalized in the anesthesia intensive care unit

You may not qualify if:

• Chronic illness that may affect pressure injury healing (malnutrition, hypertension, and diabetes)
• Discharge during the investigation process
• Death during the investigation process
• Acute cellulitis
• Severe heart failure
• Renal failure
• Tuberculosis
• Superior vena cava obstruction

Sponsors & Collaborators

• Rukiye Kokkiz: lead

MeSH Terms

Conditions

Pressure Ulcer

Condition Hierarchy (Ancestors)

Skin Ulcer; Skin Diseases; Skin and Connective Tissue Diseases

Central Study Contacts

rukiye kökkız, LECTURER

CONTACT

+90 507 140 68 98; rky_kokkiz@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: LECTURER

Study Record Dates

• First Submitted: June 19, 2026
• First Posted: July 1, 2026
• Study Start: July 1, 2026
• Primary Completion: August 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 1, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share