NCT07747974

Brief Summary

This randomized controlled trial was conducted to compare the effectiveness of Modified Constraint-Induced Movement Therapy (MCIMT) and Mirror Therapy in improving upper limb function among children with spastic hemiplegic cerebral palsy. Upper limb dysfunction, including reduced grip strength, impaired manual dexterity, and increased spasticity, limits functional independence and participation in daily activities in these children. Although both interventions are widely used in pediatric rehabilitation, direct comparative evidence remains limited. A total of 42 children aged 5-9 years diagnosed with spastic hemiplegic cerebral palsy were recruited from Akbar Kare Institute and Comprehensive Physical Rehabilitation Center, Peshawar. Participants were selected through convenience sampling and randomly allocated into two equal groups using the sealed envelope method. Group A received Modified Constraint-Induced Movement Therapy, while Group B received Mirror Therapy. Both groups received treatment for 30 minutes per session, five sessions per week, for six consecutive weeks. Grip strength was assessed using the Hand-Held Dynamometer, manual dexterity using the Box and Block Test, and spasticity using the Modified Ashworth Scale. The findings of this study provide evidence regarding the comparative effectiveness of these two rehabilitation approaches and may assist clinicians in selecting the most appropriate intervention for improving upper limb function in children with spastic hemiplegic cerebral palsy.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
2mo left

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress74%
Mar 2026Sep 2026

Study Start

First participant enrolled

March 3, 2026

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

July 31, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 5, 2026

Completed
25 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

August 5, 2026

Status Verified

June 1, 2026

Enrollment Period

6 months

First QC Date

July 31, 2026

Last Update Submit

July 31, 2026

Conditions

Spastic Hemiplegic Cerebral Palsy

Keywords

cerebral palsyupper extremity rehabilitationmirror therapymanual dexterityhand strengthConstraint-Induced Movement Therapy

Outcome Measures

Primary Outcomes (1)

  • Grip Strength

    Instrument: Hand-Held Dynamometer

    Assessment Time: Baseline and 6 Weeks

Secondary Outcomes (2)

  • Manual Dexterity

    Assessment Time: Baseline and 6 Weeks

  • Spasticity

    Assessment Time: Baseline and 6 Weeks

Study Arms (2)

Modified Constraint-Induced Movement Therapy (MCIMT)

EXPERIMENTAL

Participants received MCIMT for 30 minutes per session, five sessions per week for six weeks, together with conventional physiotherapy.

Other: Experimental

Mirror Therapy

ACTIVE COMPARATOR

Participants received Mirror Therapy for 30 minutes per session, five sessions per week for six weeks, together with conventional physiotherapy.

Other: Control

Interventions

ExperimentalOTHER

Participants received MCIMT for 30 minutes per session, five sessions per week for six weeks, together with conventional physiotherapy.

Modified Constraint-Induced Movement Therapy (MCIMT)
ControlOTHER

Participants received Mirror Therapy for 30 minutes per session, five sessions per week for six weeks, together with conventional physiotherapy.

Mirror Therapy

Eligibility Criteria

Age5 Years - 9 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Children aged 5-9 years.
  • Male and female participants.
  • Diagnosed with spastic hemiplegic cerebral palsy.
  • Modified Ashworth Scale Grade 1 or 1+.
  • Able to understand and follow verbal commands.

You may not qualify if:

  • Severe fixed hand deformity.
  • Cognitive impairment.
  • Severe visual impairment.
  • Uncontrolled seizures.
  • Previous upper limb surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ibadat International University

Islamabad, 4700, Pakistan

RECRUITING

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Hafsah Arshad, Phd*

CONTACT

03315165234hafsah.arshad@uipt.iiui.edu.pk

Laiba Khushbakht, MS( Paeds)

CONTACT

03401114118laibakhushbakhtimdad@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

July 31, 2026

First Posted

August 5, 2026

Study Start

March 3, 2026

Primary Completion (Estimated)

August 30, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

August 5, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)