Neck-to-Waist Ratio Identifies Chronic Hypertensive Phenotype and Occlusive Myocardial Infarction in Patients Presenting With Acute Coronary Syndrome

NCT07676656 | Completed

• 1 other identifier: antropometric
• Study Type: observational
• Target: 238
• Locations: 1 country
• Sites: 1

Brief Summary

aim of this study was to evaluate the relationship between multiple conventional and novel anthropometric measurements and hypertension in patients presenting to the ED with ACS and whether anthropometric indices differ according to admission BP status and evaluated the relationship between regional adiposity-related anthropometric phenotypes and cardiovascular stress response in ACS presentations. Rather than representing a general population-based study, this study evaluates the association between ACS and elevated admission BP in a population already characterized by a substantial metabolic disease burden.

Conditions

Hypertension; Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI); Obesity (Disorder)

Keywords

hypertension; acute coronary syndrome; occlusive myocardial infarction; anthropometry; obesity

Outcome Measures

Primary Outcomes (1)

• Association Between Anthropometric Phenotype and Elevated Admission Blood Pressure in Acute Coronary Syndrome

  The primary outcome was the difference in conventional and regional adiposity-related anthropometric measurements between patients with elevated admission blood pressure and those with normal admission blood pressure at emergency department presentation.

  Anthropometric measurements and blood pressure values were obtained during the index hospitalization, with anthropometric measurements performed immediately before coronary angiography or within the first 24 hours following the procedure.

Study Arms (2)

normal blood pressure at admission group

patients admitted to emergency department with normal blood pressure

elevated blood pressure at admission group

patients admitted to emergency department with elevated blood pressure

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients presenting to the ED with chest pain or anginal equivalents who were diagnosed with ACS after evaluation with physical examination, cardiac biomarkers, and imaging studies, and who were subsequently hospitalized for coronary imaging, were included in the study

You may qualify if:

• Patients presenting to the emergency department with chest pain or anginal equivalents, diagnosed with ACS, admitted to CICU for coronary angiography
• aged over 18 years

You may not qualify if:

• Patients with anatomical abnormalities in the regions where anthropometric measurements were to be performed (n=11)
• Patients with endocrinological disorders causing anatomical abnormalities of the neck, waist, or hip circumference (n=3)
• Patients with neck tumors (n=1)
• ACS patients who did not undergo coronary angiography(n=6)
• Etiologies causing secondary troponin elevation (e.g., pulmonary embolism, aortic dissection, hypoxia-related pathologies, sepsis, and anemia) (n=51)
• Mean arterial pressure \< 65 mmHg (n=9)
• Patients unable to stand upright (n=18)
• Patients with ascites (n=1)

Sponsors & Collaborators

• Ercis Sehit Rıdvan Cevik State Hospital: lead
• Ankara Etlik City Hospital: collaborator

Study Sites (1)

Etlik City hospital

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hypertension; Acute Coronary Syndrome; Obesity

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Myocardial Ischemia; Heart Diseases; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Elif Hamzaçebioğlu Kayışoğlu, MD

  erciş şehit rıdvan çevik state hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 24, 2026
• First Posted: June 30, 2026
• Study Start: February 28, 2025
• Primary Completion: February 28, 2026
• Study Completion: February 28, 2026
• Last Updated: June 30, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)