Effect of Spinal Stabilization Exercises on Epicardial Fat Tissue and Exercise Capacity in Hypertensives

NCT06083376 | Completed

• 1 other identifier: KMU-TUNCSUYGUN-003
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

It has been suggested that Epicardial Adipose Tissue (EAT) may be an adjunctive marker to classical risk factors for the presence and severity of coronary artery disease. EAT thickness is also associated with MetS and hypertension, high levels of low-density lipoprotein cholesterol and insulin resistance.Studies have shown that moderate-intensity and high-intensity aerobic exercise and resistance exercise training reduce EAT. However, aerobic and resistance exercises may be found challenging and demanding by individuals and in most cases, high or moderate intensity exercise may be considered difficult. In a study conducted in physically inactive individuals, it was concluded that there was a significant increase in heart rate and BP following spinal stabilisation exercises performed 4 days a week for a total of 8 sessions for 2 weeks, but the increase in these cardiac parameters would tend to decrease following regular exercise. In the current literature, there is no study evaluating the effect of spinal stabilisation exercise on EAT thickness, exercise capacity and cardiovascular parameters in individuals with HT. Barriers to access to healthcare services such as distance, time and cost can be overcome with technology. COVID-19 has accelerated the transition of many physiotherapy services to telerehabilitation. Evidence has shown that telerehabilitation is an effective delivery model for providing face-to-face physiotherapy services with equal or even superior outcomes, especially in musculoskeletal treatment. The aim of this study was to determine the effect of spinal stabilisation exercise with telerehabilitation on EAT and exercise capacity in individuals with HT.

Conditions

Hypertension

Keywords

Epicardial adipose tissue; Hypertension; Exercises Capacity; Telerehabilitation; spinal stabilisation exercise

Outcome Measures

Primary Outcomes (2)

• Change in epicardial fat tissue thickness after 8 weeks-24 sessions of exercise

  All patients underwent transthoracic echocardiography conducted by a single cardiologist using a Philips HD11XE (Philips Medical Systems) device in the left lateral decubitus position by the standard technique. Epicardial fat thickness was measured in the parasternal long axis imaging window, using the aortic annulus as an anatomical indicator for vertical measurement, and the widest part of the region from the right ventricular free wall to the pericardium at the end of the systole.

  baseline and 8 weeks

• Change in exercises capacity after 8 weeks-24 sessions of exercise

  The six-minute walk test (6MWT) will be administered to all participants twice on the same day, half an hour apart. Patients will rest for 10 minutes before the test is performed. Subjects will be asked to walk as fast as possible at their own walking speed for 6 minutes in a 30-meter straight corridor. Every minute during the test, standard phrases will be used to encourage the patient. At the end of the test, 6 minutes walking distance will be recorded. There is no minimum or maximum value as it depends on the person's performance. Longer walking distance indicates better functional capacity.

  baseline and 8 weeks

Secondary Outcomes (12)

• Change in blood pressure after 8 weeks-24 sessions of exercise

  baseline and 8 weeks

• Change in heart rate after 8 weeks-24 sessions of exercise

  baseline and 8 weeks

• Change in Evaluation of Spinal Stabilisation Endurance after 8 weeks-24 sessions of exercise

  baseline and 8 weeks

• Evaluation of Stabilisation Strength of Deep Spinal Muscles after 8 weeks-24 sessions of exercise

  baseline and 8 weeks

• Evaluation of Peripheral Muscle Strength after 8 weeks-24 sessions of exercise

  baseline and 8 weeks

Study Arms (2)

exercise group

EXPERIMENTAL

Other: Spinal Stabilization Exercise

control group

ACTIVE COMPARATOR

Other: physical activity counseling

Interventions

Spinal Stabilization Exercise OTHER

Spinal stability exercises are commonly used isometric and isotonic exercises. A spinal stabilization exercise training program will be applied to the exercise group participants using the telerehabilitation method (simultaneous connection) 3 days a week for 8 weeks and a total of 24 sessions.

exercise group

physical activity counseling OTHER

Control group participants will first be given initial evaluations and verbal physical activity recommendations will be given. Patients will be contacted by phone at the 2nd, 4th and 6th weeks and reminded about the importance of physical activity.

control group

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being followed up with Hypertension for at least 6 months
• Volunteering to participate in the study
• Speaking Turkish
• Being literate
• Not having participated in any structured exercise programme for at least 6 months

You may not qualify if:

• Severe valvular disease
• Having heart failure
• Having cardiomyopathy
• Myocardial infarction at least 6 months ago
• Stable or unstable angina pectoris
• Left ventricular ejection fraction below 40
• Presence of peripheral artery disease
• History of deep vein thrombosis, pulmonary embolism or stroke in the past
• Chronic kidney disease
• Having thyroid diseases
• Active infectious or inflammatory disease
• Body Mass Index \>40 kg/m2
• Having a serious psychiatric illness such as panic disorder or major depression

Sponsors & Collaborators

• Karamanoğlu Mehmetbey University: lead
• Karaman Training and Research Hospital: collaborator

Study Sites (1)

Karamanoğlu Mehmetbey University

Merkez, Karaman, Turkey (Türkiye)

Location

Related Publications (1)

• Tunc Suygun E, Suygun H, Senalp ZE, Vardar Yagli N. The effect of telerehabilitation-based core stabilization exercises on epicardial fat tissue and exercise capacity in hypertensives. Disabil Rehabil. 2025 Nov 24:1-12. doi: 10.1080/09638288.2025.2593190. Online ahead of print.

  PMID: 41283774 DERIVED

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: LECTURER

Study Record Dates

• First Submitted: October 5, 2023
• First Posted: October 16, 2023
• Study Start: December 1, 2023
• Primary Completion: October 29, 2024
• Study Completion: October 29, 2024
• Last Updated: May 2, 2025

Record last verified: 2025-04

Locations

TU (1)