NCT06635616

Brief Summary

known hypertensive patients admitted to emergency department with increased blood pressure will be evaluated in terms of antihypertensive agents given at hospital, degree of blood pressure decrease, hospital stay and laboratory and imaging tests ordered. The impact of routine oral antihypertensive agents used by the patients on these parameter will be assessed.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
350

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2024

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 8, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 10, 2024

Completed
22 days until next milestone

Study Start

First participant enrolled

November 1, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

October 10, 2024

Status Verified

September 1, 2024

Enrollment Period

1 year

First QC Date

October 8, 2024

Last Update Submit

October 8, 2024

Conditions

Keywords

hypertensionemergency medicineoral antihypertensive agents

Outcome Measures

Primary Outcomes (1)

  • routine use of oral antihypertensive agents and its effects on emergency service care

    emergency service blood pressure target achievement duration changes depending on routine oral antihypertensive agent prescribed

    from enrollment to the end of follow up duration of 7 days

Study Arms (6)

diuretics

patients prescribed diuretics for oral treatment admitted to emergency service with elevated blood pressure

Beta Blockers

patients prescribed Beta Blockers for oral treatment admitted to emergency service with elevated blood pressure

Calcium Channel Blockers

patients prescribed Calcium Channel Blockers for oral treatment admitted to emergency service with elevated blood pressure

ACE (angiotensin converting enzyme) Inhibitors

patients prescribed ACE (angiotensin converting enzyme) Inhibitors for oral treatment admitted to emergency service with elevated blood pressure

ARB( angiotensin receptor blockers)

patients prescribed ARB( angiotensin receptor blockers) for oral treatment admitted to emergency service with elevated blood pressure

combination

patients prescribed combination agents for oral treatment admitted to emergency service with elevated blood pressure

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with known hypertension admitted to emergency department with elevated blood pressure

You may qualify if:

  • Patients aged 18 and older.
  • Blood pressure measured at ≥140/80.
  • Diagnosis of essential hypertension.

You may not qualify if:

  • Pregnant patients.
  • Individuals without a prior diagnosis of hypertension.
  • Patients with end-organ damage (hypertensive emergency).
  • Patients whose routine antihypertensive agents are unavailable.
  • Patients who leave the clinic without permission, making follow-up data inaccessible.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Etlik City Hospital

Ankara, 06170, Turkey (Türkiye)

Location

Etimesgut Military Hospital

Ankara, 06790, Turkey (Türkiye)

Location

Related Publications (3)

  • Salvetti M, Paini A, Colonetti E, Tarozzi L, Bertacchini F, Aggiusti C, Stassaldi D, Rosei CA, Rosei EA, Muiesan ML. Hypertensive emergencies and urgencies: a single-centre experience in Northern Italy 2008-2015. J Hypertens. 2020 Jan;38(1):52-58. doi: 10.1097/HJH.0000000000002213.

    PMID: 31415308BACKGROUND
  • Nowicki J, Silka W, Zalustowicz A, Rajzer M, Olszanecka A. Uncontrolled hypertension and hypertensive urgency: One-year single-center emergency department experience. Kardiol Pol. 2024;82(4):407-415. doi: 10.33963/v.phj.100025. Epub 2024 Apr 12.

    PMID: 38606743BACKGROUND
  • Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Apra F, Veglio F, Milan A. Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis. J Hypertens. 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372.

    PMID: 32510905BACKGROUND

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Elif HAMZACEBIOGLU KAYISOGLU, Specialist

    Etimesgut Military Hospital

    STUDY DIRECTOR
  • Gulsen AKCAY, Ass. Prof.

    Ankara Etlik City Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gulsen AKCAY, Ass. Prof.

CONTACT

Elif HAMZACEBIOGLU KAYISOGLU, Specialist

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
30 Days
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 8, 2024

First Posted

October 10, 2024

Study Start

November 1, 2024

Primary Completion

November 1, 2025

Study Completion

November 1, 2025

Last Updated

October 10, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Locations