Development of Pain Management JITAI Content in Multiple Sclerosis and Spinal Cord Injury

NCT07663266 | Recruiting

• 2 other identifiers: HUM00290625K24AT012644-02
• Study Type: observational
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

Just-In-Time Adaptive Interventions (JITAIs) offer a framework for delivering personalized behavioral support using time-varying data to optimize the timing and type of intervention content. This project will develop the foundational components of a JITAI tailored to adults with chronic pain and either MS or SCI by drawing on symptom self-management content from existing programs (PainGuide, MyMSToolkit, and MySCIToolkit). Intervention content and delivery parameters will be refined through stakeholder engagement via structured interviews to ensure relevance, acceptability, and feasibility.

Conditions

Multiple Sclerosis; Spinal Cord Injury

Outcome Measures

Primary Outcomes (1)

• Preference

  Participant preferences for the JITAI push notification content and delivery assessed via interviews. The primary outcome will be assessed with qualitative data analyses, which will be used to inform push notification content for a JITAI to support chronic pain self-management in adults with MS and adults with SCI.

  1 day

Study Arms (1)

Interviews

This study will utilize a community engaged research approach to facilitate collaboration between participants and researchers in developing JITAI content to support pain self-management. Participants will have been formally diagnosed with either multiple sclerosis (MS) and/or spinal cord injury (SCI). Participants will review proposed JITAI content and provide feedback only to the study team.

Other: Push Notification Content

Interventions

Push Notification Content OTHER

This project will develop the foundational components of a JITAI (push notification content) tailored to adults with chronic pain and either MS or SCI by drawing on symptom self-management content from existing programs (PainGuide, MyMSToolkit, and MySCIToolkit). Intervention content and delivery parameters will be refined through stakeholder engagement via structured interviews with participants to ensure relevance, acceptability, and feasibility.

Interviews

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with chronic pain and either MS or SCI.

You may qualify if:

• Able to read and converse fluently in English
• Multiple sclerosis (MS) or Spinal Cord Injury (SCI) diagnosis
• Chronic pain ( ≥ 4 on average using a 0-10 NRS for 3-month duration)
• Access to an internet connected device with a camera and microphone for participating in virtual interview/focus group.

You may not qualify if:

• Cognitive or other impairment (e.g., hearing) that precludes study participation.

Sponsors & Collaborators

• University of Michigan: lead
• National Center for Complementary and Integrative Health (NCCIH): collaborator

Study Sites (1)

University of Michigan

Ann Arbor, Michigan, 48109, United States

RECRUITING

MeSH Terms

Conditions

Multiple Sclerosis; Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Spinal Cord Diseases; Central Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Anna Kratz

  University of Michigan

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Kristen Pickup

CONTACT

734-764-4072; knpicku@med.umich.edu

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 16, 2026
• First Posted: June 23, 2026
• Study Start: May 25, 2026
• Primary Completion: July 1, 2026
• Study Completion: July 1, 2026
• Last Updated: June 23, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)