Motivational Interviewing to Increase Physical Activity to Treat Depression in People Aging With MS or SCI

NCT00947232 | Completed

• 2 other identifiers: 36020-JH133B080024
• Study Type: interventional
• Target: 123
• Locations: 1 country
• Sites: 1

Brief Summary

This study compares two approaches to helping people who are aging with MS or SCI and are experiencing depressed mood to become more physically active. The study is carried out entirely by telephone. There is no need to travel and participants may reside anywhere within the United States. We will examine the effects of the intervention on overall physical activity, mood, pain, fatigue and general health. Participants will complete surveys over the phone throughout the study and wear an activity monitor 3 times. The study is 6 months in length and participants may receive up to $120 for their time and effort.

Conditions

Multiple Sclerosis; Spinal Cord Injury

Keywords

major depressive disorder; physical activity; aging with physical disability; motivational interviewing

Outcome Measures

Primary Outcomes (1)

• HAM-D

  17-item interview based depression severity measure

  Baseline, weeks 4, 6, 8, 12, and 24

Secondary Outcomes (1)

• International Physical Activity Questionnaire

  Baseline, weeks 4, 6, 8, 12, and 24

Study Arms (2)

Motivational interviewing

EXPERIMENTAL

Motivational interviewing for people aging with multiple sclerosis or spinal cord injury to increase physical activity and decrease depression.

Behavioral: Motivational interviewing

Education

ACTIVE COMPARATOR

Education about physical activity for people aging with multiple sclerosis or spinal cord injury to decrease depression.

Behavioral: Education

Interventions

Motivational interviewing BEHAVIORAL

Motivational interviewing, a proven counseling method that centers on individual goals and motivations, to increase exercise and decrease depression.

Motivational interviewing

Education BEHAVIORAL

Educational intervention about the benefits of physical activity to decrease depression for people aging with multiple sclerosis or spinal cord injury.

Education

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• aged at least 45 years old
• self-report diagnosis of MS or SCI
• meeting SCID requirements for Major Depressive Disorder (MDD) or dysthymia
• MS: EDSS between 4.0 and 8.0
• SCI: ASIA A-D injury level at or below C4 and they have upper extremity function sufficient to propel a manual wheelchair
• meeting PHQ-9 measure cut-off for depression by scoring more than 10 on the measure
• currently inactive (exercising less than 150 minutes per week)
• response form received from participants' doctor declaring exercise safe for the subject.

You may not qualify if:

• significant cognitive impairment
• pressure ulcers on sitting surfaces (or another condition that precludes sitting
• significant obesity (\>160% of ideal body weight)
• significant risk factors for beginning moderate physical activity measured with the PAR-Q
• response form received from participants' doctor declaring exercise unsafe for the subject
• a self-reported history of significant Uthoff's effect for those with MS
• psychiatric contraindications such as bipolar disorder, psychosis, active suicidal ideation with intent or plan, or current alcohol or drug dependence. We will include people who remain depressed but are on stable doses of antidepressant medications.

Sponsors & Collaborators

• University of Washington: lead

Study Sites (1)

University of Washington

Seattle, Washington, 98195, United States

Location

Related Links

• Website for the Aging Rehabilitation Research and Training Center

MeSH Terms

Conditions

Multiple Sclerosis; Spinal Cord Injuries; Depressive Disorder, Major; Motor Activity

Interventions

Motivational Interviewing; Educational Status

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Spinal Cord Diseases; Central Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries; Depressive Disorder; Mood Disorders; Mental Disorders; Behavior

Intervention Hierarchy (Ancestors)

Directive Counseling; Counseling; Mental Health Services; Behavioral Disciplines and Activities; Health Services; Health Care Facilities Workforce and Services; Socioeconomic Factors; Population Characteristics

Study Officials

• Charles Bombardier, PhD

  University of Washington

  PRINCIPAL INVESTIGATOR

• Mark Jensen, PhD

  University of Washington

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 24, 2009
• First Posted: July 28, 2009
• Study Start: October 1, 2009
• Primary Completion: December 1, 2012
• Study Completion: March 1, 2013
• Last Updated: May 5, 2017

Record last verified: 2017-05

Locations

US (1)