NCT07662629

Brief Summary

patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains. Programmed phsyical activity are reommended to improve these pains but effects of HYperbaric oxygen on these pain was not investigated

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable breast-cancer

Timeline
1mo left

Started May 2026

Shorter than P25 for not_applicable breast-cancer

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress74%
May 2026Sep 2026

Study Start

First participant enrolled

May 7, 2026

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

June 17, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 23, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

June 23, 2026

Status Verified

June 1, 2026

Enrollment Period

4 months

First QC Date

June 17, 2026

Last Update Submit

June 17, 2026

Conditions

Breast Cancer

Outcome Measures

Primary Outcomes (1)

  • visual analogue scale

    it self asessmant of pain level

    it will be measured after 2 months

Secondary Outcomes (10)

  • worst pain

    it will be measured after 2 months

  • pain severity

    it will be measured after 2 months

  • pain related interference

    it will be measured after 2 months

  • pain score

    it will be measured after 2 months

  • stifness score

    it will be measured after 2 months

  • +5 more secondary outcomes

Study Arms (2)

group number 1

EXPERIMENTAL

Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month.

Other: hyperbaric therapy and exercise

group number 2

ACTIVE COMPARATOR

Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month)

Other: exercise

Interventions

hyperbaric therapy and exerciseOTHER

Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly fro 2 month) and additinally received one-hour hyperbaric therapy session , five times weekly for 2 month.

group number 1
exerciseOTHER

Twenty elder survivors from breast cancer with musckolskeletal pains resultes from aromatase inhibitor intake received phsyical activity program (aerobci training on traedmill and strengtheining protcol thrice weekly for 2 month).

group number 2

Eligibility Criteria

Age65 Years - 75 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsself-representation of gender identity.
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • braest cancer survivors
  • patients receiving aramatase inhibitor drugs
  • patients with musckolskeletal pains

You may not qualify if:

  • cardiac patients
  • respiratory patients
  • renal patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Dokki, Giza Governorate, 11432, Egypt

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Hyperbaric OxygenationExercise

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Oxygen Inhalation TherapyRespiratory TherapyTherapeuticsMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ali MA Ismail, lecturer

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ali MA Ismail, lecturer

CONTACT

01005154209ali.mohamed@pt.cu.edu.eg

ali moahmed, lecturer

CONTACT

01031321109fatmaraed1994@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

Study Record Dates

First Submitted

June 17, 2026

First Posted

June 23, 2026

Study Start

May 7, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

June 23, 2026

Record last verified: 2026-06

Locations

EG(1)