The Effect of Myofascial Release Exercises on Viscoelastic Changes of the Pectoralis Major Muscle, Pain, Range of Motion and Shoulder Functionality in Individuals Receiving Adjuvant Radiotherapy After Breast Cancer Surgery

NCT06764394 | Completed

• 1 other identifier: ATADEK 2024-19/733
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Chemotherapy, hormone therapy and radiotherapy used in the treatment of breast cancer try to prevent the recurrence of cancer. In addition to the benefits of radiotherapy, such as a decrease in recurrence and an increase in long-term survival, it may have side effects that may affect the well-being and daily life activities of patients. One of the treatment modalities used to cope with treatment-related side effects is myofascial release exercises. Myofascial release exercises can help reduce adhesions caused by scar tissue and fibrosis caused by radiation. In the literature, there is no study investigating the effect of myofascial release exercises on pectoralis major muscle viscoelastic structure. For this purpose, our study aims to investigate the effect of myofascial release exercises performed in addition to home exercise programme on pectoralis major muscle viscoelastic structure, pain, range of motion and shoulder functionality.

Conditions

Breast Cancer

Keywords

myofascial release exercises, breast cancer, radiotherapy

Outcome Measures

Primary Outcomes (2)

• Tone - pectoralis major

  Myoton® PRO (Myoton Ltd, Myoton AS, Estonia) device will be used to objectively evaluate the measurement of Pectoralis Major muscle tone of the patients who will participate in the study. Myoton® PRO is a portable digital device that measures the tone with an objective and noninvasive method. A constant pre-pressure (0.18 N) is applied to the skin surface to compress the subcutaneous superficial tissues. The tension state of the tissue that characterized by the natural oscillation frequency; Hz.

  6 weeks

• Range of motion

  Shoulder range of motion will be evaluated by digital goniometer. Shoulder flexion degree, shoulder extension degree, abduction and adduction degree, internal rotation and external rotation degree will be assessed with digital goniometer. The results will be recorded in degrees.

  6 weeks

Secondary Outcomes (3)

• Pain - Visual Analogue Scale

  6 weeks

• Shoulder Pain and Disability Index- SPADI

  6 weeks

• Quality of Life- Functional Assessment of Cancer Therapy-Breast" (FACT-B)

  6 weeks

Study Arms (2)

home based exercise group

ACTIVE COMPARATOR

home-based exercise 5 days a week

Myofascial release exercise group

EXPERIMENTAL

home based exercise plus Myofascial release exercise

Other: Exercise

Interventions

Exercise OTHER

home based exercise 5 days/week

Also known as: home based exercise

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stage I-II-III defined by radiation oncologists after breast cancer surgery and who will start radiotherapy
• Breast conserving surgery or total mastectomy with axillary lymph node dissection during surgery
• No neurological or orthopaedic problems that may limit the range of motion of the shoulder joint in the preoperative evaluations,
• Individuals who volunteer to participate in the study will be included.

You may not qualify if:

• Previous breast clamp surgery on the same side or contralateral side,
• With a metastatic cancer focus,
• Post-surgical resistance, infection and open wound, pacemaker,
• Patients with a Mini Mental State Examination test score of less than 21 will be excluded from the study.

Sponsors & Collaborators

• Acibadem University: lead

Study Sites (1)

SBU. Prof. Dr. Cemil Taşçıoğlu City Hospital- Oncology Clinic

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Exercise

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asistant professor

Study Record Dates

• First Submitted: January 2, 2025
• First Posted: January 8, 2025
• Study Start: December 20, 2024
• Primary Completion: March 30, 2025
• Study Completion: May 10, 2025
• Last Updated: November 25, 2025

Record last verified: 2025-01

Locations

TU (1)