Endometrial Cavity After Conservative Management of PAS Patients by Hysteroscopy

NCT07662187 | Completed

• 1 other identifier: Soh-Med-24-05--06PD.
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to evaluate the endometrial cavity by hysteroscopy after different conservative management of placenta accrete spectrum (PAS), that has impact on the future fertility outcome and menstrual pattern of patients.

Conditions

Uterine Cavity; Conservative Management; Placenta Accreta

Outcome Measures

Primary Outcomes (1)

• Number of participants with restoration of the endometrial cavity assessed by office hysteroscopy

  Assessment of endometrial cavity restoration by office hysteroscopy 3 months after conservative management of placenta accreta spectrum.

  3 months after cesarean section

Study Arms (3)

Group I

EXPERIMENTAL

Patients underwent resection and reconstruction.

Procedure: Resection and reconstruction

Group II

EXPERIMENTAL

Patients underwent cervical eversion and pouch closure.

Procedure: Cervical eversion and pouch closure

Group III

EXPERIMENTAL

Patients underwent anterior and posterior sutures.

Procedure: Anterior and posterior sutures

Interventions

Resection and reconstruction PROCEDURE

Patients underwent resection and reconstruction.

Group I

Cervical eversion and pouch closure PROCEDURE

Patients underwent cervical eversion and pouch closure.

Group II

Anterior and posterior sutures PROCEDURE

Patients underwent anterior and posterior sutures.

Group III

Eligibility Criteria

• Age: 20 Years - 40 Years
• Gender Eligibility Details: Pregnant women with placenta Accreta
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age from 20 to 40 years.
• Pregnant women more than 28 weeks have a desire to preserve future fertility.
• Diagnosis of Placenta accreta spectrum (PAS) was evaluated by 2 D grey scale ultrasound and Doppler study of invasion of the placenta.
• History of at least previous caesarean section (CS) or any intrauterine operation like myomectomy.
• Females with history of different conservatives management methods of PAS in last three months.

You may not qualify if:

• Non placenta accreta spectrum and primigravida.
• Those who have congenital anomalies in the uterus.
• Those with bleeding tendency.
• Those women that had hysterectomy as a radical surgery.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, 82511, Egypt

Location

MeSH Terms

Conditions

Placenta Accreta

Interventions

Plastic Surgery Procedures

Condition Hierarchy (Ancestors)

Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Placenta Diseases

Intervention Hierarchy (Ancestors)

Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Sohag University, Sohag, Egypt.

Study Record Dates

• First Submitted: June 4, 2026
• First Posted: June 23, 2026
• Study Start: May 13, 2024
• Primary Completion: June 1, 2026
• Study Completion: June 1, 2026
• Last Updated: June 29, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)