NCT07660042

Brief Summary

Objectives: The aim of this study is to validate the measurements produced from a new 3D analysis using facial scans in infants with unilateral cleft lip and palate. Material and Methods: Infants with unilateral cleft lip and palate will be included in the current study. For all included patients; direct anthropometric measurements, 2D images and facial scans using intraoral scanners will be collected. Measurements produced from the 3 methods will be compared statistically to identify the validity of using the facial scans to assess nasolabial esthetics in infants with unilateral cleft lip and palate.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2024

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

June 13, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 22, 2026

Completed
Last Updated

June 22, 2026

Status Verified

June 1, 2026

Enrollment Period

2 years

First QC Date

June 13, 2026

Last Update Submit

June 17, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Nose and lip esthetics

    Evaluation of nose and lip esthetics on facial scans and photos. Clefted nostril width and height, interlabial gap and columellar length will be assessed digitally on facial scans and 2D photographs in millimeters.

    3 months

Study Arms (1)

Full Digitial NAM

EXPERIMENTAL

Infants with unilateral cleft lip and palate will be included in the current study. For all included patients; direct anthropometric measurements, 2D images and facial scans using intraoral scanners will be collected. Measurements produced from the 3 methods will be compared statistically to identify the validity of using the facial scans to assess nasolabial esthetics in infants with unilateral cleft lip and palate.

Device: F-D-NAM

Interventions

F-D-NAMDEVICE

Infants with unilateral cleft lip and palate will be included in the current study. For all included patients; direct anthropometric measurements, 2D images and facial scans using intraoral scanners will be collected. Measurements produced from the 3 methods will be compared statistically to identify the validity of using the facial scans to assess nasolabial esthetics in infants with unilateral cleft lip and palate.

Full Digitial NAM

Eligibility Criteria

Age1 Day - 2 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Infants with cleft lip and palate.

You may not qualify if:

  • Syndromes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry-Cairo University

Cairo, Giza Governorate, 00202, Egypt

Location

MeSH Terms

Conditions

Cleft Lip

Condition Hierarchy (Ancestors)

Lip DiseasesMouth DiseasesStomatognathic DiseasesMouth AbnormalitiesStomatognathic System AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

June 13, 2026

First Posted

June 22, 2026

Study Start

June 1, 2024

Primary Completion

May 30, 2026

Study Completion

May 30, 2026

Last Updated

June 22, 2026

Record last verified: 2026-06

Locations