The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI

NCT07656480 | Not Yet Recruiting

• 1 other identifier: 183551747
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Previous studies have confirmed that both acute (single) and long-term various exercise interventions can significantly improve the cognitive function of individuals with MCI. The positive effects of long-term Qigong and elastic band exercises have also been verified. There are relatively few studies on the impact of Qigong and elastic band exercises on working memory. Most studies focusing on working memory mainly target children and college students. The effect of these exercises on the elderly has not been proven, and the improvement mechanism has not been clarified either. This article mainly starts from a single exercise perspective to explore whether a single exercise can improve the VSWM of elderly individuals with MCI. From the perspective of neurophysiology, it also discusses the brain mechanism of single Qigong and elastic band exercises on the working memory of cognitively impaired elderly people, providing reference for future long-term exercise prescriptions for the treatment and prevention of Alzheimer's disease in China.

Conditions

Mild Cognitive Impairment (MCI)

Outcome Measures

Primary Outcomes (1)

• visuo-spatial working memory

  The primary research outcome pertains to visuospatial working memory, which is measured through a visuospatial working memory task paradigm. The specific paradigm is as follows: First, a "+" appears in the middle of a gray computer screen for 300 ms. Second, a 4x4 grid matrix appears at the center of the screen for 2000 ms, with 5 small black squares randomly placed within the matrix. Immediately afterwards, a blank screen is presented for 3000 ms. During this period, the participants are required to mentally visualize the probe stimulus after rotating it 90° to the left (or right). Subsequently, a 4x4 grid target stimulus is presented again for 4000 ms, and the participants need to make a judgment on the target stimulus, specifically whether it is the result of rotating the probe stimulus 90° to the left (or right), as shown in Figure 3. The entire experiment lasts approximately 8 minutes.

  From July 1, 2026, to September 1, 2026, the duration is two months.

Secondary Outcomes (1)

• EEG power value

  The total duration was two months.

Study Arms (3)

baduanjin

EXPERIMENTAL

Other: baduanjin exercise

Resistance band

EXPERIMENTAL

Other: elastic band exercises

control

NO INTERVENTION

Interventions

baduanjin exercise OTHER

Perform the 30-minute Baduanjin exercise

baduanjin

elastic band exercises OTHER

Perform 30 minutes of elastic band exercises

Resistance band

Eligibility Criteria

• Age: 60 Years - 74 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- Include the elderly population aged between 60 and 74 years old.
• \- Includes individuals with cognitive impairments. The patients or informants report experiencing memory decline and having certain cognitive dysfunction (MoCA score = 18-25 points).
• \- Including individuals who have controlled diabetes and/or cardiovascular diseases to a stable state.
• \- Irregular exercise with the ability to complete a certain amount of physical activities.
• \- Normal vision and hearing.

You may not qualify if:

• \- Patients with moderate to severe cognitive impairment, mental illness or other neurodegenerative diseases (such as Parkinson's dementia, stroke, frontotemporal degeneration, vascular dementia, Lewy body dementia, etc.).
• \- Long-term or recent use of psychotropic drugs, drugs that affect physical activity ability, cholinergic inhibitors, etc.
• \- Regular exercise habit .
• \- There are serious muscle disorders, or there has been an injury to the lower limbs within the previous six months, making it impossible to stand for a long time or to stand at all.
• \- Severe cardiovascular disease.

Sponsors & Collaborators

• qiu chen: lead

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Central Study Contacts

chen qiu

CONTACT

86+13964805297; q13964805297@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: student

Study Record Dates

• First Submitted: May 27, 2026
• First Posted: June 18, 2026
• Study Start: July 1, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 14, 2026
• Last Updated: June 18, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share