Efficacy of Cognitive Stimulation Therapy Integrated With Stress Reduction Intervention for Adults With Mild Cognitive Impairment

NCT07469618 | Not Yet Recruiting

• 1 other identifier: D/14/FIMS
• Study Type: interventional
• Target: 12
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to determine if integrating a culturally congruent indigenous stress reduction intervention into Cognitive Stimulation Therapy (CST) enhances cognitive outcomes in Pakistani adults with Mild Cognitive Impairment (MCI).

Conditions

Mild Cognitive Impairment (MCI)

Outcome Measures

Primary Outcomes (1)

• Change in Montreal Cognitive Assessment (MoCA) total score from baseline to 7 weeks

  The Montreal Cognitive Assessment (MoCA) will be used to assess overall cognitive functioning, including attention, memory, language, executive functions, and visuospatial abilities. The MoCA total score ranges from 0 to 30, with higher scores indicating better cognitive functioning. Assessments will be conducted at baseline and after completion of the 7-week intervention period.

  7 weeks

Study Arms (3)

Cognitive Stimulation Therapy integrated with Stress Reduction Intervention

EXPERIMENTAL

Participants receive Cognitive Stimulation Therapy integrated with Stress Reduction Intervention for 7 weeks.

Behavioral: Cognitive Stimulation Therapy integrated with Stress Reduction Intervention

Cognitive Stimulation Therapy (CST)

ACTIVE COMPARATOR

Participants receive Cognitive Stimulation Therapy sessions for 7 weeks.

Behavioral: Cognitive Stimulation Therapy

Control Group

NO INTERVENTION

Participants will not receive any structured therapy during the 7 week study period.

Interventions

Cognitive Stimulation Therapy integrated with Stress Reduction Intervention BEHAVIORAL

Participants in this Arm will receive Cognitive Stimulation Therapy integrated with Stress Reduction Intervention for 7 weeks, combining structured cognitive exercises targeting memory, attention, and problem-solving with guided stress reduction techniques.

Cognitive Stimulation Therapy integrated with Stress Reduction Intervention

Cognitive Stimulation Therapy BEHAVIORAL

Participants in this Arm will attend Cognitive Stimulation Therapy sessions only for 7 weeks, including structured cognitive exercises targeting memory, attention, and problem-solving in a group format.

Cognitive Stimulation Therapy (CST)

Eligibility Criteria

• Age: 45 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 45 years and above
• Individuals with education up to Matric
• Individuals who obtain a score lower than 23 on Montreal Cognitive Assessment (MoCA) suggesting the presence of cognitive decline.
• Individuals who obtain a score of 14 or more on the Perceived Stress Scale suggesting increased levels of perceived stress (moderate and high)
• Individuals who obtain score ranged from 13 to 25 (Poor to Adequate) on Quality of Life in Alzheimer's Disease (Qol-AD)

You may not qualify if:

• Diagnosis of dementia or major neurocognitive disorder
• Presence of severe psychiatric illness (e.g., psychosis, major depressive episode)
• Significant hearing or visual impairments that interfere with participation
• Currently undergoing psychological or cognitive therapy
• Any neurological condition that may interfere with cognitive assessment (e.g., stroke, Parkinson's disease)

Sponsors & Collaborators

• University of the Punjab: lead

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Student

Study Record Dates

• First Submitted: March 4, 2026
• First Posted: March 13, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: March 13, 2026

Record last verified: 2026-03