Non-pharmacological Interventions for People With Mild Cognitive Impairment in the Community

NCT07703267 | Not Yet Recruiting DMC

• 1 other identifier: 81251000
• Study Type: interventional
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

Mild cognitive impairment (MCI) may increase the risk of dementia. This study will evaluate an 8-week community-family mutual support intervention for adults aged 60 years or older with MCI. Participants will be randomly assigned to an intervention group or a control group. The control group will receive routine community care, while the intervention group will additionally receive cognitive training, health education, family support, mutual support activities, and individualized feedback. Cognitive function, daily functioning, emotional status, and social support will be assessed before and after the intervention.

Conditions

Mild Cognitive Impairment (MCI)

Outcome Measures

Primary Outcomes (1)

• Change in Cognitive Function Assessed by the Montreal Cognitive Assessment (MoCA)

  From enrollment to the end of treatment at 8 weeks

Secondary Outcomes (2)

• Change From Baseline in Social Support Rating Scale (SSRS) Total Score

  From enrollment to the end of treatment at 8 weeks

• Change From Baseline in Patient Health Questionnaire-9 (PHQ-9) Total Score

  From enrollment to the end of treatment at 8 weeks

Study Arms (2)

Community-Family Mutual Support Intervention

EXPERIMENTAL

Participants will receive routine community care plus an 8-week community-family mutual support intervention based on social support theory. The intervention includes health education, cognitive training, emotional self-monitoring, family involvement, mutual support between participating families, group activities, and individualized feedback.

Other: Community-Family Mutual Support Intervention

Routine Community Care

ACTIVE COMPARATOR

Participants will receive routine community care, including standard health education and usual community-based health services, during the 8-week study period. They will not receive the community-family mutual support intervention.

Other: Routine Community Care

Interventions

Community-Family Mutual Support Intervention OTHER

Participants will receive an 8-week community-family mutual support intervention in addition to routine community care. Guided by social support theory, the program integrates informational, emotional, instrumental, and appraisal support. It includes MCI-related health education, cognitive training, physical activity guidance, emotional self-monitoring, home-based practice with family assistance, mutual support between paired families, group activities, and individualized feedback. The intervention will be delivered through community-based sessions and supported home activities by trained researchers and community nurses.

Community-Family Mutual Support Intervention

Routine Community Care OTHER

Participants will receive routine community care, including standard health education and usual community-based health services, during the 8-week study period. They will not receive the community-family mutual support intervention.

Routine Community Care

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 60 years or older.
• Meets the diagnostic criteria for mild cognitive impairment, including subjective cognitive decline, objective impairment in at least one cognitive domain, relatively preserved activities of daily living, and no diagnosis of dementia.
• Has lived in the study community for at least 6 months.
• Has completed primary school or above and is able to read and write.
• Is able to communicate and complete the study assessments and intervention activities.
• Voluntarily participates and provides written informed consent.

You may not qualify if:

• Unable to communicate effectively.
• Has severe visual or hearing impairment that prevents participation.
• Has dementia, schizophrenia, or another severe psychiatric disorder.
• Has a serious or unstable physical illness that prevents participation in the intervention.
• Is currently participating in another cognitive training or similar intervention study.

Sponsors & Collaborators

• Anhui Medical University: lead
• The First Affiliated Hospital of Anhui Medical University: collaborator

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Central Study Contacts

Yiran Yue

CONTACT

8617333266696; yueyiran1@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 7, 2026
• First Posted: July 14, 2026
• Study Start: July 28, 2026
• Primary Completion (Estimated): September 28, 2026
• Study Completion (Estimated): October 28, 2026
• Last Updated: July 14, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share