NCT07654543

Brief Summary

This study evaluated and compared the therapeutic efficacy of combining Dry Cupping therapy with the Muscle Energy Technique (MET) against each intervention applied independently, focusing on three core parameters: Neck Disability Index (NDI), Craniovertebral Angle (CVA), and Sagittal Shoulder-C7 Angle (SSA).

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for not_applicable

Timeline
0mo left

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress90%
Mar 2026Jun 2026

Study Start

First participant enrolled

March 1, 2026

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 13, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 17, 2026

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 18, 2026

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Expected
Last Updated

June 17, 2026

Status Verified

June 1, 2026

Enrollment Period

4 months

First QC Date

June 13, 2026

Last Update Submit

June 13, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Neck Disability Index (NDI)

    Perceived functional limitations resulting from regional impairment were measured using the validated Arabic version of the NDI questionnaire. This instrument evaluates 10 clinical sections (including activities of daily living, concentration, and pain profiles) scored from 0 to 5 per item, yielding a cumulative score out of 50. Higher aggregate indices represent greater functional disability.

    At baseline and re assessed following 8 weeks

  • craniovertebral angle (CVA)

    This biomechanical index reflects the architectural severity of forward head posture. It is defined as the angle formed between a horizontal line drawn through the spinous process of C7 and an intersecting line extending from the tragus of the ear to the C7 landmark. CVA was measured using precision digital photogrammetry via the Kinovea software application.

    At baseline and re assessed following 8 weeks

  • Sagittal Shoulder-C7 Angle (SSA)

    This geometric marker quantifies shoulder roundedness and anterior protraction. It is formed by the intersection of a horizontal reference line passing through the lateral aspect of the acromion with a line drawn from the C7 spinous process to the lateral acromion. SSA was measured using precision digital photogrammetry via the Kinovea software application.

    At baseline and re assessed following 8 weeks

Study Arms (4)

Group A (Combined group)

EXPERIMENTAL

Group A (Combined group): This group of nineteen subjects received combined dry cupping therapy, Muscle energy techniques, and conventional physical therapy.

Procedure: combined therapy teatment

Group B (Cupping group)

EXPERIMENTAL

Group B (Cupping group): This group of nineteen subjects received dry cupping therapy and conventional physical therapy.

Procedure: cupping therapy group

Group C (MET group)

EXPERIMENTAL

Group C (MET group): This group of nineteen subjects received Muscle energy techniques and conventional physical therapy.

Procedure: muscle energy techniques group

Group D (Control group)

ACTIVE COMPARATOR

Group D (Control group): This group of nineteen subjects received conventional physical therapy alone

Procedure: control group

Interventions

19 subjects received combined dry cupping therapy, Muscle energy technique, and conventional physical therapy for eight weeks. 1. Dry cupping was applied to the regional hypertonic target sites. Standard plastic cups ranging from 25 to 50 mm were placed directly over each subject's levator scapulae trigger point (SI-14) and upper trapezius trigger point (GB-21) bilaterally. The treatment duration was set at exactly 8 minutes per session. 2. Muscle Energy Technique The Post-Isometric Relaxation (PIR) manual protocol targeted the hypertonic muscles of the upper crossed syndrome quadrant, including the upper trapezius, levator scapulae, sternocleidomastoid, scalenes, and suboccipital groups. Participants were placed in a supine position on the treatment table with their head free from the edge of the plinth, supported by the physical therapist. 3. conventional physical therapy treatment

Group A (Combined group)

19 subjects received combined dry cupping therapy and conventional physical therapy for eight weeks. 1. Dry cupping was applied to the regional hypertonic target sites. Standard plastic cups ranging from 25 to 50 mm were placed directly over each subject's levator scapulae trigger point (SI-14) and upper trapezius trigger point (GB-21) bilaterally. The treatment duration was set at exactly 8 minutes per session. 2. conventional physical therapy treatment

Group B (Cupping group)

19 subjects received combined Muscle energy technique, and conventional physical therapy for eight weeks. 1. Muscle Energy Technique The Post-Isometric Relaxation (PIR) manual protocol targeted the hypertonic muscles of the upper crossed syndrome quadrant, including the upper trapezius, levator scapulae, sternocleidomastoid, scalenes, and suboccipital groups. Participants were placed in a supine position on the treatment table with their head free from the edge of the plinth, supported by the physical therapist. 2. conventional physical therapy treatment

Group C (MET group)
control groupPROCEDURE

19 subjects received only conventional physical therapy for eight weeks.

Group D (Control group)

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • The exact diagnostic criteria required a baseline craniovertebral angle (CVA) of less than 48 degrees.
  • a sagittal shoulder-C7 angle (SSA) of less than 52 degrees.

You may not qualify if:

  • acute post-surgical conditions
  • structural spinal deformities (e.g., severe fixed structural scoliosis)
  • cervical radiculopathy, or localized dermal infections contradicting cupping application.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type Preus

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
lecturer of physical therapy

Study Record Dates

First Submitted

June 13, 2026

First Posted

June 17, 2026

Study Start

March 1, 2026

Primary Completion

June 18, 2026

Study Completion (Estimated)

June 30, 2026

Last Updated

June 17, 2026

Record last verified: 2026-06

Locations