NCT07698392

Brief Summary

The purpose of the study will be to investigate dynamic neuromuscular stabilization versus National American Academy of Sports Medicine (NASM) corrective exercises on pain, functional disability, cranio-vertebral angle, forward shoulder angle, and thoracic kyphosis in upper cross syndrome.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
23mo left

Started Nov 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 13, 2026

Completed
4 months until next milestone

Study Start

First participant enrolled

November 1, 2026

Expected
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2027

1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2028

Last Updated

July 13, 2026

Status Verified

July 1, 2026

Enrollment Period

3 months

First QC Date

July 8, 2026

Last Update Submit

July 8, 2026

Conditions

Upper Crossed SyndromeUpper Cross SyndromeUpper Crossed Syndorme

Outcome Measures

Primary Outcomes (1)

  • Neck pain intensity

    Neck pain intensity will be measured through Numerical pain rating scale. A scale from 0 to 10, with 0 indicating no pain and 10 signifying excruciating pain.

    At baseline at the first session and reassessed at the end of six weeks of intervention.

Secondary Outcomes (4)

  • Neck disability

    At baseline at the first session and after 6 weeks of intervention.

  • Craniovertebral angle

    At baseline and after 6 weeks of intervention

  • Forward shoulder angle

    At baseline and after 6 weeks of intervention

  • Thoracic kyphosis angle

    At baseline and after 6 weeks of intervention

Study Arms (3)

Dynamic neuromuscular stabilization

EXPERIMENTAL

Dynamic neuromuscular stabilization involves precise co-activation of the intrinsic muscles of the spine which forms the Integrated spinal stabilization system (ISSS) and includes cervical flexors and extensors, diaphragm, transversus abdominis, multifidus and pelvic floor. Participants will receive DNS for 6 weeks.

Other: Dynamic neuromuscular stabilization

Corrective exercises

EXPERIMENTAL

National Academy of sports medicine corrective exercises that involve 4 steps : First: Inhibition for tight muscles Second: Lengthening for tight muscles Third: Activation for weak muscles fourth: Intergration to retrain all muscles through functionally progressive movements using integrated dynamic movements. Participants will receive NASM corrective exercises for 6 weeks.

Other: NASM corrective exercises

Combined Dynamic neuromuscular stabilization and corrective exercises group

EXPERIMENTAL

Participants will receive both DNS and NASM for 6 weeks.

Other: Dynamic neuromuscular stabilizationOther: NASM corrective exercises

Interventions

Dynamic neuromuscular stabilizationOTHER

Dynamic neuromuscular stabilization involves precise co-activation of the intrinsic muscles of the spine which forms the Integrated spinal stabilization system (ISSS) and includes cervical flexors and extensors, diaphragm, transverses abdominis, multifidus and pelvic floor.

Combined Dynamic neuromuscular stabilization and corrective exercises groupDynamic neuromuscular stabilization
NASM corrective exercisesOTHER

It is corrective exercise protocol, which includes four phases, i.e. inhibit, lengthen, activate, and integrate stage

Combined Dynamic neuromuscular stabilization and corrective exercises groupCorrective exercises

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Having non-specfic neck Pain.
  • Patients having a CVA of \< 52 .
  • Forward shoulder angle \> 52 degrees.

You may not qualify if:

  • Participants having conditions such as osteoporosis, blood disease, congestive heart disease, cancer, severe skin sensitization, major mental disease, and frozen shoulder, will be excluded from the study. Neck pain has a specific underlying pathology such as fractures, rheumatoid arthritis, osteoporosis, or whiplash injuries as well as neck pain associated with radiculopathy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Outpatient clinic at faculty of physical therapy - Cairo University

Cairo, Cairo Governorate, 11432, Egypt

Location

MeSH Terms

Conditions

Oculocerebral hypopigmentation syndrome type Preus

Study Officials

  • Karima A Hassan, PhD

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Passant M Assistant lecturer, MSc

CONTACT

01004139949passant.moustafa@cu.edu.eg

Nesreen F Lecturer, PhD

CONTACT

01127283925dr_nesreenfawzy@cu.edu.eg

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecturer

Study Record Dates

First Submitted

July 8, 2026

First Posted

July 13, 2026

Study Start (Estimated)

November 1, 2026

Primary Completion (Estimated)

February 1, 2027

Study Completion (Estimated)

September 30, 2028

Last Updated

July 13, 2026

Record last verified: 2026-07

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)