Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
1 other identifier
interventional
52
1 country
1
Brief Summary
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 2, 2026
CompletedStudy Start
First participant enrolled
June 3, 2026
CompletedFirst Posted
Study publicly available on registry
June 17, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 3, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
September 10, 2026
June 17, 2026
June 1, 2026
3 months
June 2, 2026
June 16, 2026
Conditions
Outcome Measures
Primary Outcomes (2)
Pain Intensity
Measured using the Numeric Pain Rating Scale
baseline, 3rd week, and 8th week.
Functional Status and Symptom Severity
Measured using the Boston Carpal Tunnel Questionnaire
baseline, 3rd week, and 8th week
Study Arms (3)
Combined Intervention Group
EXPERIMENTALParticipants in this group will receive a combination of Neuromobilization techniques and tendon gliding exercises
Neuromobilization Group
ACTIVE COMPARATORParticipants in these groups will receive Neuromobilization techniques targeting the median nerve.
Tendon Gliding Exercise Group
ACTIVE COMPARATORwill receive tendon Gliding exercises targeting the median nerve
Interventions
will receive a combination of Neuromobilization techniques and tendon gliding exercises
will receive Neuromobilization techniques targeting the median nerve.
will receive tendon Gliding exercises targeting the median nerve
Eligibility Criteria
You may qualify if:
- Symptoms of CTS (pain, paresthesia in the area of hand innervated by the median nerve)
- First and Second Trimester Pregnant women.
- Mild to Moderate CTS patients.
- Individuals experiencing wrist pain for a duration of at least 6-8 weeks without a history of trauma or specific diagnosis (e.g., fracture, arthritis).
- Pain rated between 3 and 5 on (NPRS).
- Present neurological disorders (e.g., carpal tunnel syndrome, cervical radiculopathy).
- No prior physical therapy treatment for wrist pain in the last 3-6 months
You may not qualify if:
- History of traumatic injury, fracture, or surgery to the wrist or hand.
- Diagnosis of systemic diseases affecting the wrist (e.g., rheumatoid arthritis, gout, or diabetes-related neuropathy).
- Any skin condition or infection around the wrist that would contraindicate physical therapy.
- Third Trimester Pregnant women
- Individuals with serious cardiovascular or metabolic disorders.
- patients currently undergoing other treatments specifically targeting CTS (e.g., steroid injections)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Dr. Akbar Niazi teaching Hospital
Islamabad, ICT, Pakistan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 2, 2026
First Posted
June 17, 2026
Study Start
June 3, 2026
Primary Completion (Estimated)
September 3, 2026
Study Completion (Estimated)
September 10, 2026
Last Updated
June 17, 2026
Record last verified: 2026-06
Data Sharing
- IPD Sharing
- Will not share