Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome

NCT05905107 | Completed

• 1 other identifier: REC_FSD_00325
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

Carpal tunnel syndrome is a compressive neuropathy of median nerve in the fascial tunnel at wrist which causes pain, numbness ,and tingling in the extremities. Common treatment options used in the treatment of carpal tunnel syndrome are conservative and surgical treatment option is better, this question is still a topic requiring more and more clinical trials. Neuromobilisation described by Butler is one of the treatment options which are used in the treatment of carpal tunnel syndrome in conjunction with other conservative measures. This proposed study will find out the effectiveness of Neuromobilisation in treatment of carpal tunnel syndrome. As there is very little evidence available which Neuromobilisation technique is effective and what are the types of patients which can get benefit from this technique. This study will find out the effect of Neuromobilisation in patients suffering from carpal tunnel syndrome of non traumatic origin. This is a randomized clinical trial. Target population is patients suffering from carpal tunnel syndrome of non-traumatic origin. Data will be collected from District Headquarter Hospital Faisalabad. This study will include 56 participants according to the selection criteria. The participants will be randomly divided into two groups through sealed opaque envelop method. Group A will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. Group B will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. The Statistical analysis will be performed through SPSS Software 21.

Conditions

Carpal Tunnel Syndrome

Outcome Measures

Primary Outcomes (3)

• Pain at wrist joint

  Pain will be assessed by using Numerical Pain Rating Scale Pain will be assessed by using Numerical Pain Rating Scale

  4 weeks

• Wrist Range of Movement at wrist joint

  Range of motion will be assessed by using Goniometer

  4 weeks

• Functional Ability at wrist joint

  Functional Ability will be assessed by using Boston Carpal tunnel syndrome

  4 weeks

Study Arms (2)

Interventional Group A

EXPERIMENTAL

These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. For this, participants will be given a comfortable supine lying position. ULTT method will be implemented to the ipsilateral upper limb given in the table below

Other: Neurodynamic Slider Technique from Proximal to Distal

Interventional Group B

ACTIVE COMPARATOR

These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. For this, participants will be given a comfortable supine lying position. ULTT method will be implemented to the ipsilateral upper limb

Other: Neurodynamic Slider Technique from Distal to Proximal

Interventions

Neurodynamic Slider Technique from Proximal to Distal OTHER

Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck

Interventional Group A

Neurodynamic Slider Technique from Distal to Proximal OTHER

Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck

Interventional Group B

Eligibility Criteria

• Age: 25 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients positive for provocative test ( Phalen's test, Wrist decompression test and tinnel test).

You may not qualify if:

• Inflammation around the wrist
• Tumor around the wrist
• Rheumatoid Arthritis
• Osteoporosis
• Joint Hypermobility

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

District Headquarters Hospital

Faisalābad, Punjab Province, 38000, Pakistan

Location

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Study Officials

• Sahreen Anwar, Ph.D

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 9, 2023
• First Posted: June 15, 2023
• Study Start: January 4, 2023
• Primary Completion: August 30, 2023
• Study Completion: August 30, 2023
• Last Updated: November 20, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)