NCT07646665

Brief Summary

The aim of the current project is to use deuterium-labelled glucose to assess exogenous glucose oxidation rates during exercise at moderate and high intensity.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
4mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress7%
Jun 2026Sep 2026

Study Start

First participant enrolled

June 8, 2026

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

June 9, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 15, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2026

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

June 15, 2026

Status Verified

June 1, 2026

Enrollment Period

2 months

First QC Date

June 9, 2026

Last Update Submit

June 9, 2026

Conditions

Exercise Metabolism

Outcome Measures

Primary Outcomes (1)

  • Total exogenous glucose oxidation rate

    Total exogenous glucose oxidation rate (g/h)

    Measured over 120 mins

Secondary Outcomes (2)

  • Exogenous glucose oxidation rate during moderate intensity exercise

    90 minutes

  • Exogenous glucose oxidation rate during high intensity exercise

    30 minutes

Other Outcomes (6)

  • Blood glucose concentrations

    120 minutes

  • Blood lactate concentrations

    120 minutes

  • Blood bicarbonate concentrations

    120 minutes

  • +3 more other outcomes

Study Arms (1)

Glucose

EXPERIMENTAL

Glucose ingestion durign exercise at 90 g.h labelled with U13C and D7 glucose.

Other: glucose

Interventions

glucoseOTHER

Glucose ingestion at 90 g/h labelled with U13C and D7 glucose

Glucose

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Endurance trained
  • Aged 18 to 65 years

You may not qualify if:

  • Contraindications to exercise
  • Unable to complete 2 hours of continuous cycling

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Bath

Bath, Bath, BA2 7AY, United Kingdom

Location

MeSH Terms

Interventions

Glucose

Intervention Hierarchy (Ancestors)

HexosesMonosaccharidesSugarsCarbohydrates

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Nutrition and Metabolism

Study Record Dates

First Submitted

June 9, 2026

First Posted

June 15, 2026

Study Start

June 8, 2026

Primary Completion (Estimated)

July 30, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

June 15, 2026

Record last verified: 2026-06

Locations

GB(1)