Hemodialysis Catheter Complications in the Emergency Department Versus Hemodialysis Unit

NCT07645365 | Completed

• 1 other identifier: 2024-324
• Study Type: observational
• Target: 398
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency department and those who underwent catheter insertion in the hemodialysis unit. The study was conducted at Antalya Training and Research Hospital. Adult patients aged 18 years and older who underwent hemodialysis catheter insertion in either the emergency department or the nephrology hemodialysis unit were included. A total of 398 patients were enrolled between December 1, 2024, and December 1, 2025. Demographic and clinical data were collected, and catheter-related complications occurring within 10 days after catheter insertion were assessed using hospital records and follow-up data.

Conditions

Hemodialysis Catheter Complication; Catheter Thrombosis; Catheter-Related Infections; Hemodialysis Vascular Access

Keywords

Catheter-related infection; Dialysis catheter complications; Emergency department; Hemodialysis catheter

Outcome Measures

Primary Outcomes (2)

• Incidence of Catheter-Related Infection

  The incidence of catheter-related infection will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter-related infection will be recorded based on clinical evaluation, laboratory findings when available, and hospital records during the 10-day follow-up period after catheter insertion.

  Within 10 days after hemodialysis catheter insertion

• Incidence of Catheter Thrombosis

  The incidence of catheter thrombosis will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter thrombosis will be recorded based on clinical evaluation and hospital records during the 10-day follow-up period after catheter insertion.

  Within 10 days after hemodialysis catheter insertion

Study Arms (2)

Emergency Department Hemodialysis Catheter Group

Adult patients who underwent temporary hemodialysis catheter insertion in the emergency department. Participants were followed for 10 days after catheter insertion to assess the development of catheter thrombosis and catheter-related infection.

Hemodialysis Unit Catheter Group

Adult patients who underwent temporary hemodialysis catheter insertion in the nephrology hemodialysis unit. Participants were followed for 10 days after catheter insertion to assess the development of catheter thrombosis and catheter-related infection.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of adult patients aged 18 years and older who underwent temporary hemodialysis catheter insertion in either the emergency department or the nephrology hemodialysis unit at Antalya Training and Research Hospital between December 1, 2024, and December 1, 2025. Participants were followed for 10 days after catheter insertion to evaluate the development of catheter thrombosis and catheter-related infection.

You may qualify if:

• Patients aged 18 years or older
• Patients who underwent temporary hemodialysis catheter insertion in the emergency department
• Patients who underwent temporary hemodialysis catheter insertion in the hemodialysis unit
• Patients who agreed to participate in the study

You may not qualify if:

• Patients younger than 18 years of age
• Patients who did not agree to participate in the study
• Patients with known platelet function disorder
• Patients with hematologic diseases, including malignancy
• Immunosuppressed patients

Sponsors & Collaborators

• Antalya Health Sciences University: lead

Study Sites (1)

University of Health Sciences, Antalya Training and Research Hospital

Antalya, konyaaltı, 07100, Turkey (Türkiye)

Location

Related Publications (3)

• Buetti N, Timsit JF. Management and Prevention of Central Venous Catheter-Related Infections in the ICU. Semin Respir Crit Care Med. 2019 Aug;40(4):508-523. doi: 10.1055/s-0039-1693705. Epub 2019 Oct 4.

  PMID: 31585477 BACKGROUND

• Leblanc M, Bosc JY, Paganini EP, Canaud B. Central venous dialysis catheter dysfunction. Adv Ren Replace Ther. 1997 Oct;4(4):377-89. doi: 10.1016/s1073-4449(97)70026-8.

  PMID: 9356690 BACKGROUND

• Fisher M, Golestaneh L, Allon M, Abreo K, Mokrzycki MH. Prevention of Bloodstream Infections in Patients Undergoing Hemodialysis. Clin J Am Soc Nephrol. 2020 Jan 7;15(1):132-151. doi: 10.2215/CJN.06820619. Epub 2019 Dec 5.

  PMID: 31806658 BACKGROUND

MeSH Terms

Conditions

Catheter-Related Infections; Emergencies

Condition Hierarchy (Ancestors)

Infections; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• MEHMET AKCIMEN

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

• MURAT DUYAN

  University of Health Sciences, Antalya Training and Research Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 9, 2026
• First Posted: June 12, 2026
• Study Start: December 1, 2024
• Primary Completion: December 11, 2025
• Study Completion: December 11, 2025
• Last Updated: June 12, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)